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  1. Patients with somatostatin receptor-expressing neuroendocrine tumours can be treated with intravenously administered 177Lu-octreotate. Few patients are cured with the present protocol due to the current dose limi...

    Authors: Viktor Sandblom, Ingun Ståhl, Roger Olofsson Bagge and Eva Forssell-Aronsson

    Citation: EJNMMI Physics 2017 4:3

    Content type: Original research

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  2. The aim of the study is to assess accuracy of activity quantification of 177Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 2...

    Authors: Carlos F. Uribe, Pedro L. Esquinas, Jesse Tanguay, Marjorie Gonzalez, Emilie Gaudin, Jean-Mathieu Beauregard and Anna Celler

    Citation: EJNMMI Physics 2017 4:2

    Content type: Original research

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  3. The use of integrated PET-MR offers new opportunities for comprehensive assessment of cardiac morphology and function. However, little is known on the quantitative accuracy of cardiac PET imaging with integrat...

    Authors: Tanja Kero, Jonny Nordström, Hendrik J. Harms, Jens Sörensen, Håkan Ahlström and Mark Lubberink

    Citation: EJNMMI Physics 2017 4:1

    Content type: Original research

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  4. The convolution approach to thyroid time-activity curve (TAC) data fitting with a gamma distribution convolution (GDC) TAC model following bolus intravenous injection is presented and applied to 99mTc-MIBI data. ...

    Authors: Carl A. Wesolowski, Surajith N. Wanasundara, Michal J. Wesolowski, Belkis Erbas and Paul S. Babyn

    Citation: EJNMMI Physics 2016 3:31

    Content type: Original research

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  5. [18F]HX4 is a promising new PET tracer developed to identify hypoxic areas in tumor tissue. This study analyzes [18F]HX4 kinetics and assesses the performance of simplified methods for quantification of [18F]HX4 ...

    Authors: E. E. Verwer, C. M. L. Zegers, W. van Elmpt, R. Wierts, A. D. Windhorst, F. M. Mottaghy, P. Lambin and R. Boellaard

    Citation: EJNMMI Physics 2016 3:30

    Content type: Original research

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  6. Quantitative single photon emission computed tomography (SPECT) is challenging, especially for pancreatic beta cell imaging with 111In-exendin due to high uptake in the kidneys versus much lower uptake in the nea...

    Authors: Wietske Woliner-van der Weg, Laura N. Deden, Antoi P. W. Meeuwis, Maaike Koenrades, Laura H. C. Peeters, Henny Kuipers, Geert Jan Laanstra, Martin Gotthardt, Cornelis H. Slump and Eric P. Visser

    Citation: EJNMMI Physics 2016 3:29

    Content type: Original Research

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  7. Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) is now a routine procedure for the management of cancer patients. Intravenous administration of FDG is sometimes halted due to troubles. In suc...

    Authors: Kenta Sakaguchi, Makoto Hosono, Tomomi Imamura, Naomi Takahara, Misa Hayashi, Yuko Yakushiji, Kazunari Ishii, Tatsuro Uto and Takamichi Murakami

    Citation: EJNMMI Physics 2016 3:28

    Content type: Original research

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  8. The impact of increased energy resolution of cadmium–zinc–telluride (CZT) cameras on the assessment of left ventricular function under dual-isotope conditions (99mTc and 123I) remains unknown.

    Authors: Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini and Alain Manrique

    Citation: EJNMMI Physics 2016 3:27

    Content type: Original research

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  9. The point spread function (PSF) of positron emission tomography (PET) depends on the position across the field of view (FOV). Reconstruction based on PSF improves spatial resolution and quantitative accuracy. ...

    Authors: Taisuke Murata, Kenta Miwa, Noriaki Miyaji, Kei Wagatsuma, Tomoyuki Hasegawa, Keiichi Oda, Takuro Umeda, Takashi Iimori, Yoshitada Masuda, Takashi Terauchi and Mitsuru Koizumi

    Citation: EJNMMI Physics 2016 3:26

    Content type: Original article

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  10. Both enantiomers of [18F]flubatine are new radioligands for neuroimaging of α4β2 nicotinic acetylcholine receptors with positron emission tomography (PET) exhibiting promising pharmacokinetics which makes them at...

    Authors: Mathias Kranz, Bernhard Sattler, Solveig Tiepolt, Stephan Wilke, Winnie Deuther-Conrad, Cornelius K. Donat, Steffen Fischer, Marianne Patt, Andreas Schildan, Jörg Patt, René Smits, Alexander Hoepping, Jörg Steinbach, Osama Sabri and Peter Brust

    Citation: EJNMMI Physics 2016 3:25

    Content type: Original research

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  11. Recent advancements in PET instrumentation have made the non-invasive assessment of cardiovascular function in small animals a reality. The majority of small animal PET systems use stationary detector gantries...

    Authors: Paul R. Territo, Amanda A. Riley, Brian P. McCarthy and Gary D. Hutchins

    Citation: EJNMMI Physics 2016 3:24

    Content type: Short communication

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  12. While fluorodeoxyglucose (FDG) and amyloid PET is valuable for patient management, research, and clinical trial of therapeutics on Alzheimer’s disease, the specific details of the PET scanning method including...

    Authors: Yasuhiko Ikari, Go Akamatsu, Tomoyuki Nishio, Kenji Ishii, Kengo Ito, Takeshi Iwatsubo and Michio Senda

    Citation: EJNMMI Physics 2016 3:23

    Content type: Original research

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  13. For tumour imaging with PET, the literature proposes to administer a patient-specific FDG activity that depends quadratically on a patient’s body weight. However, a practical approach on how to implement such ...

    Authors: Daniëlle Koopman, Jochen A. C. van Osch, Pieter L. Jager, Carlijn J. A. Tenbergen, Siert Knollema, Cornelis H. Slump and Jorn A. van Dalen

    Citation: EJNMMI Physics 2016 3:22

    Content type: Original research

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  14. 177Lu-DOTATATE is a valuable treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. Though well tolerated in general, bone marrow to...

    Authors: Johanna Svensson, Tobias Rydén, Linn Hagmarker, Jens Hemmingsson, Bo Wängberg and Peter Bernhardt

    Citation: EJNMMI Physics 2016 3:21

    Content type: Original research

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  15. The search for novel image contrasts has been a major driving force in the magnetic resonance (MR) research community, in order to gain further information on the body’s physiological and pathological conditions.

    Authors: B. Wu, G. Warnock, M. Zaiss, C. Lin, M. Chen, Z. Zhou, L. Mu, D. Nanz, R. Tuura and G. Delso

    Citation: EJNMMI Physics 2016 3:19

    Content type: Review

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  16. The purpose of this study is to specify a simple procedure for a robust data conversion of radioactivity value between plastic scintillator (PL) and NaI scintillator (NaI) devices.

    Authors: Takeshi Hara, Tadahiko Ishihara, Takahiko Asano, Masayuki Matsuo, Tetsuro Katafuchi and Hiroshi Fujita

    Citation: EJNMMI Physics 2016 3:18

    Content type: Short communication

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  17. The use of selective internal radiation therapy (SIRT) is rapidly increasing, and the need for quantification and dosimetry is becoming more widespread to facilitate treatment planning and verification. The ai...

    Authors: Jonathan I. Gear, Craig Cummings, Allison J. Craig, Antigoni Divoli, Clive D. C. Long, Michael Tapner and Glenn D. Flux

    Citation: EJNMMI Physics 2016 3:17

    Content type: Original research

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  18. The recent spread of positron emission tomography-computed tomography (PET/CT) poses extremity dosimetry challenges. The question arose whether the radiation dose measured by the ring thermoluminescent dosimet...

    Authors: Fabien Salesses, Paul Perez, Aline E. Maillard, Julie Blanchard, Sabine Mallard and Laurence Bordenave

    Citation: EJNMMI Physics 2016 3:16

    Content type: Original research

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  19. Somatostatin analogue-based radionuclide therapy with 177Lu-DOTATATE is an important treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. In addition to the ki...

    Authors: Johanna Svensson, Linn Hagmarker, Tobias Magnander, Bo Wängberg and Peter Bernhardt

    Citation: EJNMMI Physics 2016 3:15

    Content type: Original research

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  20. The purpose of this study was twofold: to evaluate the quantitative stability of a SPECT/CT gamma camera over time and to determine if daily flood acquisitions can reliably serve as calibration factors for qua...

    Authors: Wendy A. McDougald, Robert S. Miyaoka, Adam M. Alessio, Robert L. Harrison and Thomas K. Lewellen

    Citation: EJNMMI Physics 2016 3:14

    Content type: Original research

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  21. The study aims to develop and validate an automatic delineation method for estimating red bone marrow (RM) activity concentration and absorbed dose in 89Zr positron emission tomography/computed tomography (PET/CT...

    Authors: N.E. Makris, R. Boellaard, C.W. Menke, A.A. Lammertsma and M.C. Huisman

    Citation: EJNMMI Physics 2016 3:13

    Content type: Original research

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  22. Patient-specific absorbed dose calculations for molecular radiotherapy require accurate activity quantification. This is commonly derived from Single-Photon Emission Computed Tomography (SPECT) imaging using a...

    Authors: Andrew P. Robinson, Jill Tipping, David M. Cullen, David Hamilton, Richard Brown, Alex Flynn, Christopher Oldfield, Emma Page, Emlyn Price, Andrew Smith and Richard Snee

    Citation: EJNMMI Physics 2016 3:12

    Content type: Original Research

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  23. We present a quick and easy method to perform quantitatively accurate PET scans of typical water-filled PET plastic shell phantoms on the Siemens Biograph mMR PET/MR system.

    Authors: Sune H. Keller, Björn Jakoby, Susanne Svalling, Andreas Kjaer, Liselotte Højgaard and Thomas L. Klausen

    Citation: EJNMMI Physics 2016 3:11

    Content type: Short communication

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  24. A brain single-photon emission computed tomography (SPECT) system using cadmium telluride (CdTe) solid-state detectors was previously developed. This CdTe-SPECT system is suitable for simultaneous dual-radionu...

    Authors: Wataru Takeuchi, Atsuro Suzuki, Tohru Shiga, Naoki Kubo, Yuichi Morimoto, Yuichiro Ueno, Keiji Kobashi, Kikuo Umegaki and Nagara Tamaki

    Citation: EJNMMI Physics 2016 3:10

    Content type: Original research

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  25. The limited spatial resolution of the clinical PET scanners results in image blurring and does not allow for accurate quantification of very thin or small structures (known as partial volume effect). In cardiac i...

    Authors: Anna Turco, Johan Nuyts, Olivier Gheysens, Jürgen Duchenne, Jens-Uwe Voigt, Piet Claus and Kathleen Vunckx

    Citation: EJNMMI Physics 2016 3:9

    Content type: Original Research

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  26. Integrated PET/MRI with hyperpolarized 13C magnetic resonance spectroscopic imaging (13C-MRSI) offers simultaneous, dual-modality metabolic imaging. A prerequisite for the use of simultaneous imaging is the absen...

    Authors: Adam E. Hansen, Flemming L. Andersen, Sarah T. Henriksen, Alexandre Vignaud, Jan H. Ardenkjaer-Larsen, Liselotte Højgaard, Andreas Kjaer and Thomas L. Klausen

    Citation: EJNMMI Physics 2016 3:7

    Content type: Original research

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  27. CATI is a French initiative launched in 2010 to handle the neuroimaging of a large cohort of subjects recruited for an Alzheimer’s research program called MEMENTO. This paper presents our test protocol and res...

    Authors: Marie-Odile Habert, Sullivan Marie, Hugo Bertin, Moana Reynal, Jean-Baptiste Martini, Mamadou Diallo, Aurélie Kas and Régine Trébossen

    Citation: EJNMMI Physics 2016 3:6

    Content type: Original research

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  28. Dopamine transporter (DaT) imaging (DaTSCAN) is useful for the differential diagnosis of parkinsonian syndromes. Visual evaluation of DaTSCAN images represents the generally accepted diagnostic method, but it ...

    Authors: Antonio Augimeri, Andrea Cherubini, Giuseppe Lucio Cascini, Domenico Galea, Maria Eugenia Caligiuri, Gaetano Barbagallo, Gennarina Arabia and Aldo Quattrone

    Citation: EJNMMI Physics 2016 3:4

    Content type: Original research

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  29. While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already built in the early 1980s, limited clinical studies were acquired on these scanners. PET was still a research tool, a...

    Authors: S. Vandenberghe, E. Mikhaylova, E. D’Hoe, P. Mollet and J. S. Karp

    Citation: EJNMMI Physics 2016 3:3

    Content type: Review

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  30. Obtaining the arterial input function (AIF) from image data in dynamic positron emission tomography (PET) examinations is a non-invasive alternative to arterial blood sampling. In simultaneous PET/magnetic res...

    Authors: Thies H. Jochimsen, Vilia Zeisig, Jessica Schulz, Peter Werner, Marianne Patt, Jörg Patt, Antje Y. Dreyer, Johannes Boltze, Henryk Barthel, Osama Sabri and Bernhard Sattler

    Citation: EJNMMI Physics 2016 3:2

    Content type: Original Research

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  31. Low uptake ratios, high noise, poor resolution, and low contrast all combine to make the detection of neuroendocrine liver tumours by 111In-octreotide single photon emission tomography (SPECT) imaging a challenge...

    Authors: Tobias Magnander, E. Wikberg, J. Svensson, P. Gjertsson, B. Wängberg, M. Båth and Peter Bernhardt

    Citation: EJNMMI Physics 2016 3:1

    Content type: Original research

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  32. Recently, significant interest in 44Sc as a tracer for positron emission tomography (PET) imaging has been observed. Unfortunately, the co-emission by 44Sc of high-energy γ rays (E γ = ...

    Authors: Rafał Walczak, Seweryn Krajewski, Katarzyna Szkliniarz, Mateusz Sitarz, Kamel Abbas, Jarosław Choiński, Andrzej Jakubowski, Jerzy Jastrzębski, Agnieszka Majkowska, Federica Simonelli, Anna Stolarz, Agnieszka Trzcińska, Wiktor Zipper and Aleksander Bilewicz

    Citation: EJNMMI Physics 2015 2:33

    Content type: Original research

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  33. A feasibility study was done to assess the capability of digital silicon photomultipliers to measure the Cherenkov luminescence emitted by a β source. Cherenkov luminescence imaging (CLI) is possible with a charg...

    Authors: Esther Ciarrocchi, Nicola Belcari, Alberto Del Guerra, Simon R. Cherry, Adrienne Lehnert, William C. J. Hunter, Wendy McDougald, Robert S. Miyaoka and Paul E. Kinahan

    Citation: EJNMMI Physics 2015 2:32

    Content type: Original Research

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  34. Small-animal imaging has become an important technique for the development of new radiotracers, drugs and therapies. Many laboratories have now a combination of different small-animal imaging systems, which ar...

    Authors: Christian Vanhove, Jens P. Bankstahl, Stefanie D. Krämer, Eric Visser, Nicola Belcari and Stefaan Vandenberghe

    Citation: EJNMMI Physics 2015 2:31

    Content type: Teaching file

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  35. Authors: Ana Mota, Vesna Cuplov, Ivana Drobnjak, John Dickson, Julien Bert, Ninon Burgos, Jorge Cardoso, Marc Modat, Sebastien Ourselin, Jonathan Schott, Kjell Erlandsson, Brian Hutton and Kris Thielemans

    Citation: EJNMMI Physics 2015 2:30

    Content type: Erratum

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    The original article was published in EJNMMI Physics 2015 2:A44

  36. The purpose of the study is to evaluate the physical performance of a Biograph mCT Flow 64-4R PET/CT system (Siemens Healthcare, Germany) and to compare clinical image quality in step-and-shoot (SS) and contin...

    Authors: Ivo Rausch, Jacobo Cal-González, David Dapra, Hans Jürgen Gallowitsch, Peter Lind, Thomas Beyer and Gregory Minear

    Citation: EJNMMI Physics 2015 2:26

    Content type: Original research

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  37. The aim of this study was to develop and validate an automated method for extracting forward stroke volume (FSV) using indicator dilution theory directly from dynamic positron emission tomography (PET) studies...

    Authors: Hendrik Johannes Harms, Lars Poulsen Tolbod, Nils Henrik Stubkjær Hansson, Tanja Kero, Lovisa Holm Orndahl, Won Yong Kim, Tomas Bjerner, Kirsten Bouchelouche, Henrik Wiggers, Jørgen Frøkiær and Jens Sörensen

    Citation: EJNMMI Physics 2015 2:25

    Content type: Original research

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  38. Radionuclide therapy can be individualized by performing dosimetry. To determine absorbed organ doses in 177Lu-DOTATATE therapy, three methods based on activity concentrations are currently in use: the small volu...

    Authors: Mattias Sandström, Ezgi Ilan, Anna Karlberg, Silvia Johansson, Nanette Freedman and Ulrike Garske-Román

    Citation: EJNMMI Physics 2015 2:24

    Content type: Original research

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  39. The purpose of this study was to evaluate the utility of bellows-based respiratory compensation and navigated hepatobiliary phase imaging to correct for respiratory motion in the setting of dedicated liver PET...

    Authors: Thomas A. Hope, Emily F. Verdin, Emily K. Bergsland, Michael A. Ohliger, Carlos U. Corvera and Eric K. Nakakura

    Citation: EJNMMI Physics 2015 2:21

    Content type: Original research

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  40. Advances in gamma camera technology and the emergence of a number of new theranostic radiopharmaceutical pairings have re-awakened interest in in vivo quantification with single-photon-emitting radionuclides. ...

    Authors: Dale L. Bailey, Thomas M. Hennessy, Kathy P. Willowson, E. Courtney Henry, David L.H. Chan, Alireza Aslani and Paul J. Roach

    Citation: EJNMMI Physics 2015 2:20

    Content type: Original research

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  41. Non-uniformity influences the interpretation of nuclear medicine based images and consequently their use in treatment planning and monitoring. However, no standardised method for evaluating and ranking heterog...

    Authors: Jonas Grafström, Hanna-Stina Ahlzén and Sharon Stone-Elander

    Citation: EJNMMI Physics 2015 2:19

    Content type: Original research

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  42. In integrated PET/MR hybrid imaging the evaluation of PET performance characteristics according to the NEMA standard NU 2–2007 is challenging because of incomplete MR-based attenuation correction (AC) for phan...

    Authors: Susanne Ziegler, Bjoern W. Jakoby, Harald Braun, Daniel H. Paulus and Harald H. Quick

    Citation: EJNMMI Physics 2015 2:18

    Content type: Original research

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