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EJNMMI Physics

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  1. Content type: Original research

    Peptide receptor radionuclide therapy (PRRT) with [177Lu]-DOTA-TATE is an effective treatment of neuroendocrine tumors (NETs). After each cycle of treatment, patient dosimetry evaluates the radiation dose to the ...

    Authors: Alexandre Chicheportiche, Faozi Artoul, Arnon Schwartz, Simona Grozinsky-Glasberg, Amichay Meirovitz, David J. Gross and Jeremy Godefroy

    Citation: EJNMMI Physics 2018 5:10

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  2. Content type: Original research

    Matched attenuation maps are vital for obtaining accurate and reproducible kinetic and static parameter estimates from PET data. With increased interest in PET/CT imaging of diffuse lung diseases for assessing...

    Authors: Beverley F. Holman, Vesna Cuplov, Lynn Millner, Raymond Endozo, Toby M. Maher, Ashley M. Groves, Brian F. Hutton and Kris Thielemans

    Citation: EJNMMI Physics 2018 5:14

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  3. Content type: Original research

    SPECT quantification is important for dosimetry in targeted radionuclide therapy (TRT) and the calibration of SPECT images is a crucial stage for image quantification. The current standardized calibration prot...

    Authors: Adrien Halty, Jean-Noël Badel, Olga Kochebina and David Sarrut

    Citation: EJNMMI Physics 2018 5:11

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  4. Content type: Original research

    Camera calibration, which translates reconstructed count map into absolute activity map, is a prerequisite procedure for quantitative SPECT imaging. Both planar and tomographic scans using different phantom ge...

    Authors: Wei Zhao, Pedro L. Esquinas, Xinchi Hou, Carlos F. Uribe, Marjorie Gonzalez, Jean-Mathieu Beauregard, Yuni K. Dewaraja and Anna Celler

    Citation: EJNMMI Physics 2018 5:8

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  5. Content type: Original research

    A newly introduced PET/CT scanner (Discovery Meaningful Insights—DMI, GE Healthcare) includes the silicon photomultiplier (SiPM) with time-of-flight (TOF) technology first used in the GE SIGNA PET/MRI. In this...

    Authors: Ida Sonni, Lucia Baratto, Sonya Park, Negin Hatami, Shyam Srinivas, Guido Davidzon, Sanjiv Sam Gambhir and Andrei Iagaru

    Citation: EJNMMI Physics 2018 5:9

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  6. Content type: Original research

    Yttrium-90 (90Y) radioembolization involves the intra-arterial delivery of radioactive microspheres to treat hepatic malignancies. Though this therapy involves careful pre-treatment planning and imaging, little i...

    Authors: Nichole M. Maughan, Mootaz Eldib, David Faul, Maurizio Conti, Mattijs Elschot, Karin Knešaurek, Francesca Leek, David Townsend, Frank P. DiFilippo, Kimberly Jackson, Stephan G. Nekolla, Mathias Lukas, Michael Tapner, Parag J. Parikh and Richard Laforest

    Citation: EJNMMI Physics 2018 5:7

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  7. Content type: Original research

    The performance of a prototype novel digital single-photon emission computed tomography (SPECT) camera with multiple pixelated CZT detectors and high sensitivity collimators (Digital SPECT; Valiance X12 protot...

    Authors: Elinor Goshen, Leonid Beilin, Eli Stern, Tal Kenig, Ronen Goldkorn and Simona Ben-Haim

    Citation: EJNMMI Physics 2018 5:6

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  8. Content type: Original research

    Single-photon emission computed tomography (SPECT) imaging is an important diagnostic tool for the early detection of the loss of nigrostriatal dopaminergic neurons in Parkinson’s disease (PD) and similar neur...

    Authors: M. K. Stam, E. E. Verwer, J. Booij, S. M. Adriaanse, C. M. de Bruin and T. C. de Wit

    Citation: EJNMMI Physics 2018 5:4

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  9. Content type: Original research

    Nuclear medicine imaging of neuroendocrine tumours is performed either by SPECT/CT imaging, using 111In-octreotide or by PET/CT imaging using 68Ga-radiolabelled somatostatin analogs. These imaging techniques will...

    Authors: L. Jönsson, A. Stenvall, E. Mattsson, E. Larsson, A. Sundlöv, T. Ohlsson and C. Hindorf

    Citation: EJNMMI Physics 2018 5:5

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  10. Content type: Original research

    Both cardiac and respiratory motions bias the kinetic parameters measured by dynamic PET. The aim of this study was to perform a realistic positron emission tomography-magnetic resonance (PET-MR) simulation st...

    Authors: Rong Guo, Yoann Petibon, Yixin Ma, Georges El Fakhri, Kui Ying and Jinsong Ouyang

    Citation: EJNMMI Physics 2018 5:3

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  11. Content type: Original research

    The aim of this study was to investigate the deadtime (DT) effects that are present in 177Lu images acquired after radionuclide therapy injection, assess differences in DT based on the full spectrum and the photo...

    Authors: Carlos F. Uribe, Pedro L. Esquinas, Marjorie Gonzalez, Wei Zhao, Jesse Tanguay and Anna Celler

    Citation: EJNMMI Physics 2018 5:2

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  12. Content type: Original research

    Full Monte Carlo (MC)-based SPECT reconstructions have a strong potential for correcting for image degrading factors, but the reconstruction times are long. The objective of this study was to develop a highly ...

    Authors: T. Rydén, J. Heydorn Lagerlöf, J. Hemmingsson, I. Marin, J. Svensson, M. Båth, P. Gjertsson and P. Bernhardt

    Citation: EJNMMI Physics 2018 5:1

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  14. Content type: Original research

    PET-MRI is under investigation as a new strategy for quantitative myocardial perfusion imaging. Consideration is required as to the maximum scanner count rate in order to limit dead-time losses resulting from ...

    Authors: Jim O’ Doherty, Zacharias Chalampalakis, Paul Schleyer, Muhummad Sohaib Nazir, Amedeo Chiribiri and Paul K. Marsden

    Citation: EJNMMI Physics 2017 4:31

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  15. Content type: Original research

     Several criteria exist to identify the optimal model for quantification of tracer kinetics. The purpose of this study was to evaluate the correspondence in kinetic model preference identification for brain PE...

    Authors: Sandeep S. V. Golla, Sofie M. Adriaanse, Maqsood Yaqub, Albert D. Windhorst, Adriaan A. Lammertsma, Bart N. M. van Berckel and Ronald Boellaard

    Citation: EJNMMI Physics 2017 4:30

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  16. Content type: Original research

    Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availabili...

    Authors: Katarina Sjögreen Gleisner, Emiliano Spezi, Pavel Solny, Pablo Minguez Gabina, Francesco Cicone, Caroline Stokke, Carlo Chiesa, Maria Paphiti, Boudewijn Brans, Mattias Sandström, Jill Tipping, Mark Konijnenberg and Glenn Flux

    Citation: EJNMMI Physics 2017 4:28

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  17. Content type: Original research

    Semi-quantification methods are well established in the clinic for assisted reporting of (I123) Ioflupane images. Arguably, these are limited diagnostic tools. Recent research has demonstrated the potential fo...

    Authors: Jonathan Christopher Taylor and John Wesley Fenner

    Citation: EJNMMI Physics 2017 4:29

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  18. Content type: Original research

    The European directive on basic safety standards (Council directive 2013/59 Euratom) mandates dosimetry-based treatment planning for radiopharmaceutical therapies. The directive comes into operation February 2...

    Authors: Caroline Stokke, Pablo Minguez Gabiña, Pavel Solný, Francesco Cicone, Mattias Sandström, Katarina Sjögreen Gleisner, Carlo Chiesa, Emiliano Spezi, Maria Paphiti, Mark Konijnenberg, Matt Aldridge, Jill Tipping, Michael Wissmeyer, Boudewijn Brans, Klaus Bacher, Carsten Kobe…

    Citation: EJNMMI Physics 2017 4:27

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  19. Content type: Original research

    Quantitative measurement of myocardial blood flow (MBF) is of increasing interest in the clinical assessment of patients with suspected coronary artery disease (CAD). 15O-water positron emission tomography (PET) ...

    Authors: Jonny Nordström, Tanja Kero, Hendrik Johannes Harms, Charles Widström, Frank A. Flachskampf, Jens Sörensen and Mark Lubberink

    Citation: EJNMMI Physics 2017 4:26

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  20. Content type: Original research

    In the planning of selective internal radiation therapy (SIRT) for liver cancer treatment, one major aspect is to determine the prescribed activity and to estimate the resulting absorbed dose inside normal liv...

    Authors: Nadine Spahr, Philipp Schilling, Smita Thoduka, Nasreddin Abolmaali and Andrea Schenk

    Citation: EJNMMI Physics 2017 4:25

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  21. Content type: Original research

    Technetium-99m-hydrazinonicotinamide-Tyr3-octreotide (99mTc-HYNIC-TOC) is recognized as a promising radiopharmaceutical for diagnosing neuroendocrine tumors (NETs). However, 99mTc-HYNIC-TOC dosimetry has been inv...

    Authors: Xinchi Hou, Bozena Birkenfeld, Hanna Piwowarska-Bilska and Anna Celler

    Citation: EJNMMI Physics 2017 4:24

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  22. Content type: Opinion article

    To date, there is no published detailed checklist with parameters referencing the DICOM tag information with respect to the quality control (QC) of PET/CT scans. The aims of these guidelines are to provide the...

    Authors: Ivalina Hristova, Ronald Boellaard, Paul Galette, Lalitha K. Shankar, Yan Liu, Sigrid Stroobants, Otto S. Hoekstra and Wim J.G. Oyen

    Citation: EJNMMI Physics 2017 4:23

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  23. Content type: Original research

    We have previously developed a novel and highly consistent PET segmentation algorithm using a multi-level Otsu method (MO-PET). The aim of this study was to evaluate the reliability of MO-PET compared to conve...

    Authors: Inki Lee, Hyung-Jun Im, Meiyappan Solaiyappan and Steve Y. Cho

    Citation: EJNMMI Physics 2017 4:22

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  24. Content type: Original research

    Implementation of PET/CT in diagnosis of primary prostate cancer (PCa) requires a profound knowledge about the tracer, preferably from a quantitative evaluation. Direct visual comparison of PET/CT slices to wh...

    Authors: F. Schiller, T. Fechter, C. Zamboglou, A. Chirindel, N. Salman, C.A. Jilg, V. Drendel, M. Werner, P.T. Meyer, A.-L. Grosu and M. Mix

    Citation: EJNMMI Physics 2017 4:21

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  25. Content type: Original research

    Developments in single photon emission tomography instrumentation and reconstruction methods present a potential for decreasing acquisition times. One of such recent options for myocardial perfusion imaging (M...

    Authors: Eero Hippeläinen, Teemu Mäkelä, Touko Kaasalainen and Erna Kaleva

    Citation: EJNMMI Physics 2017 4:20

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