Original research
Implementation of PET/CT in diagnosis of primary prostate cancer (PCa) requires a profound knowledge about the tracer, preferably from a quantitative evaluation. Direct visual comparison of PET/CT slices to wh...
EJNMMI Physics 2017 4:21
Published on: 17 August 2017
Original research
Developments in single photon emission tomography instrumentation and reconstruction methods present a potential for decreasing acquisition times. One of such recent options for myocardial perfusion imaging (M...
EJNMMI Physics 2017 4:20
Published on: 19 July 2017
Original research
A prototype anthropomorphic head and neck phantom has been designed to simulate the adult head and neck anatomy including some internal organs and tissues of interest, such as thyroid gland and sentinel lymph ...
EJNMMI Physics 2017 4:19
Published on: 6 July 2017
Original Research
Robust quantitative analysis in positron emission tomography (PET) and in single-photon emission computed tomography (SPECT) typically requires the time-activity curve as an input function for the pharmacokine...
EJNMMI Physics 2017 4:18
Published on: 2 June 2017
Original research
This study evaluates the consistency of PET evaluation response criteria in solid tumours (PERCIST) and European Organisation for Research and Treatment of Cancer (EORTC) classification across different recons...
EJNMMI Physics 2017 4:17
Published on: 30 May 2017
Original research
The correction of γ-photon attenuation in PET-MRI remains a critical issue, especially for bone attenuation. This problem is of great importance for brain studies due to the density of the skull. Current techn...
EJNMMI Physics 2017 4:16
Published on: 2 May 2017
Commentary
The year, 2016, marked the 75th anniversary of Dr. Saul Hertz first using radioiodine to treat a patient with thyroid disease. In November of 1936, a luncheon was held of the faculty of Harvard Medical School ...
EJNMMI Physics 2017 4:15
Published on: 27 April 2017
Review
Cerenkov luminescence imaging (CLI) is a novel imaging modality to study charged particles with optical methods by detecting the Cerenkov luminescence produced in tissue. This paper first describes the physica...
EJNMMI Physics 2017 4:14
Published on: 11 March 2017
Original research
A phantom in combination with an imaging protocol was developed to measure the limit of small lesion detection on different PET systems. Seven small spheres with inner diameters ranging from 3.95 up to 15.43 m...
EJNMMI Physics 2017 4:13
Published on: 4 March 2017
Original Research
Accurate PET quantification demands attenuation correction (AC) for both patient and hardware attenuation of the 511 keV annihilation photons. In hybrid PET/MR imaging, AC for stationary hardware components su...
EJNMMI Physics 2017 4:12
Published on: 1 March 2017
Original research
Monolithic scintillators read out by arrays of photodetectors represent a promising solution to obtain high spatial resolution and the depth of interaction (DOI) of the annihilation photon. We have recently in...
EJNMMI Physics 2017 4:11
Published on: 16 February 2017
Original research
Our aim was to characterize the influence of time-of-flight (TOF) and point spread function (PSF) recovery corrections, as well as ordered subset expectation maximization (OSEM) reconstruction parameters, in 82Rb...
EJNMMI Physics 2017 4:10
Published on: 15 February 2017
Short communication
Our aim was to evaluate if a recently introduced TOF PET system with digital photon counting technology (Philips Healthcare), potentially providing an improved image quality over analogue systems, can fulfil E...
EJNMMI Physics 2017 4:9
Published on: 31 January 2017
Original research
[123I]FP-CIT is a well-established radiotracer for the diagnosis of dopaminergic degenerative disorders. The European Normal Control Database of DaTSCAN (ENC-DAT) of healthy controls has provided age and gender-s...
EJNMMI Physics 2017 4:8
Published on: 28 January 2017
Original research
In order to obtain a reliable 177Lu-DOTATATE therapy dosimetry, it is crucial to acquire accurate and precise activity measurements with the radionuclide calibrator, the SPECT/CT camera, and the NaI(Tl) well coun...
EJNMMI Physics 2017 4:7
Published on: 26 January 2017
Original Research
Radiolabeled OTSA101, a monoclonal antibody targeting synovial sarcoma (SS) developed by OncoTherapy Science, was used to treat relapsing SS metastases following a theranostic procedure: in case of significant 11...
EJNMMI Physics 2017 4:6
Published on: 18 January 2017
Original research
PET image reconstruction methods include modeling of resolution degrading phenomena, often referred to as point-spread function (PSF) reconstruction. The aim of this study was to develop a clinically relevant ...
EJNMMI Physics 2017 4:5
Published on: 13 January 2017
Short communication
Simultaneous cardiac perfusion studies are an increasing trend in PET-MR imaging. During dynamic PET imaging, the introduction of gadolinium-based MR contrast agents (GBCA) at high concentrations during a dual...
EJNMMI Physics 2017 4:4
Published on: 13 January 2017
Original research
Patients with somatostatin receptor-expressing neuroendocrine tumours can be treated with intravenously administered 177Lu-octreotate. Few patients are cured with the present protocol due to the current dose limi...
EJNMMI Physics 2017 4:3
Published on: 9 January 2017
Original research
The aim of the study is to assess accuracy of activity quantification of 177Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 2...
EJNMMI Physics 2017 4:2
Published on: 7 January 2017
Original research
The use of integrated PET-MR offers new opportunities for comprehensive assessment of cardiac morphology and function. However, little is known on the quantitative accuracy of cardiac PET imaging with integrat...
EJNMMI Physics 2017 4:1
Published on: 6 January 2017
Original research
The convolution approach to thyroid time-activity curve (TAC) data fitting with a gamma distribution convolution (GDC) TAC model following bolus intravenous injection is presented and applied to 99mTc-MIBI data. ...
EJNMMI Physics 2016 3:31
Published on: 16 December 2016
Original research
[18F]HX4 is a promising new PET tracer developed to identify hypoxic areas in tumor tissue. This study analyzes [18F]HX4 kinetics and assesses the performance of simplified methods for quantification of [18F]HX4 ...
EJNMMI Physics 2016 3:30
Published on: 12 December 2016
Original Research
Quantitative single photon emission computed tomography (SPECT) is challenging, especially for pancreatic beta cell imaging with 111In-exendin due to high uptake in the kidneys versus much lower uptake in the nea...
EJNMMI Physics 2016 3:29
Published on: 7 December 2016
Original research
Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) is now a routine procedure for the management of cancer patients. Intravenous administration of FDG is sometimes halted due to troubles. In suc...
EJNMMI Physics 2016 3:28
Published on: 14 November 2016
