Articles

PET/MR and SPECT/MR multimodal imaging constructs: Direct radiolabelling of silica shell iron oxide nanorods for use in liver imaging and potential for hyperthermia therapy

Authors: Haylay Bignell

Authentically radiolabelled Mn(II) complexes as bimodal PET/MR tracers

Authors: Christian Vanasschen, Marie Brandt, Johannes Ermert, Bernd Neumaier and Heinz H Coenen

Correlation between arterial spin labeling MRI and dynamic FDG on PET-MR in Alzheimer’s disease and non-Alzhiemer’s disease patients

Authors: David Douglas, Maged Goubran, Eugene Wilson, Guofan Xu, Pragya Tripathi, Dawn Holley, Steven Chao, Max Wintermark, Andrew Quon, Michael Zeineh, Minal Vasanawala and Greg Zaharchuk

Epileptogenic focus localization: a new approach

Authors: Vânia Tavares, André Santos Ribeiro, Carlos Capela, Luís Cerqueira and Hugo Alexandre Ferreira

Determination of position and shape of flexible mri surface coils using the Microsoft Kinect for attenuation correction in PET/MRI

Authors: Lynn Frohwein, Mirco He, Florian Buther and Klaus Safers

The potential of TOF PET-MRI for reducing artifacts in PET images

Authors: Andrei Iagaru, Ryogo Minamimoto, Craig Levin, Amid Barkhodari, Mehran Jamali, Dawn Holley and Zaharchuk Greg

Brain connectivity study of brain tumor patients using MR-PET data: preliminary results

Authors: Ana Carina Mendes, Andre Santos Ribeiro, Ana Maria Oros-Peusquens, Karl Josef Langen, Jon Shah and Hugo Alexandre Ferreira

Assessment of PET & ASL metabolism in the hippocampal subfields of MCI and AD using simultaneous PET-MR

Authors: Maged Goubran, David Douglas, Steven Chao, Andrew Quon, Pragya Tripathi, Dawn Holley, Minal Vasanawala, Greg Zaharchuk and Michael Zeineh

Simultaneous trimodal MR-PET-EEG imaging for the investigation of resting state networks in humans

Authors: Irene Neuner, Joerg Mauler, Jorge Arrubla, Elena Rota Kops, Lutz Tellmann, Jurgen Scheins, Hans Herzog, Karl Josef Langen and Jon Shah

Assess PET/MR in diagnosis of disease in comparison with PET/CT

Authors: Jianhua Yan, Jason Chu-Chern Lim, Hoi Yin loi, John Totoman, Arvind Kumar Sinha, Swee Titan Quek and David Townsend

Stability of MR brain-perfusion measurement using arterial spin labeling

Authors: Jan Petr, Frank Hofheinz, Ivan Platzek, Georg Schramm and Jorg Van Den Hoff

Imaging patients with breast and prostate cancers using combined 18F NaF/18F FDG and TOF simultaneous PET/ MRI

Authors: Andrei Iagaru, Ryogo Minamimoto, Mehran Jamali, Amir Barkodhodari, Sanjiv Sam Gambhir and Shreyas Vasanawala

Dedicated brain PET system of PET/MR for brain research

Authors: Li Cheng, Yaqiang Liu, Tianyu Ma, Shi Wang, Qingyang Wei and Tianpeng Xu

Compatibility of metal additive manufactured tungsten collimator for SPECT/MRI integration

Authors: Amine M Samudi, Karen Van Audenhaege, Gunter Vermeeren, Luc Martens, Roel Van Holen and Wout Joseph

Measuring the mutual effects between a CZT detector and MRI for the development of a simultaneous MBI/MRI insert

Authors: Ashley Tao, Troy Farncombe and Michael Noseworthy

MRC-SPECT-DF: an MR-Compatible SPECT system with Dual-FOV collimation design for microscopic SPECT imaging

Authors: Xiaochun Lai, Chin-tu Chen and Ling-Jian Meng

Assessment of the quality of brain regions and neuroimaging metrics as biomarkers of Alzheimer’s Disease

Authors: Tânia Faria Vaz, Filipa Lucena, Joana Pé-Leve, André Santos Ribeiro, Luís Lacerda, Nuno da Silva, David Nutt, John McGonigle and Hugo Alexandre Ferreira

Establishment of an open database of realistic simulated data for evaluation of partial volume correction techniques in brain PET/MR

Authors: Ana Mota, Vesna Cuplov, Jonathan Schott, Brian Hutton, Kris Thielemans, Ivana Drobnjak, John Dickson, Julien Bert, Ninon Burgos, Jorge Cardoso, Marc Modat, Sebastien Ourselin and Kjell Erlandsson

Rapid workflow of mMR PET list-mode data processing using CUDA

Authors: Pawel Markiewicz, Kris Thielemans, David Atkinson, Simon Arridge, Brian Hutton and Sebastien Ourselin

Alternating-direction method of multipliers estimation of attenuation and activity distributions in time-of-flight flat-panel positron emission tomography

Authors: Yueh Hsu and Cheng-Ying Chou

Attenuation correction for hybrid MR/PET scanners: a comparison study

Authors: Elena Rota Kops, Andre Santos Ribeiro, Liliana Caldeira, Hubertus Hautzel, Mathias Lukas, Gerald Antoch, Christoph Lerche and Jon Shah

A theoretical comparison of position estimation methods for determining the interaction position of gamma rays in monolithic scintillators

Authors: Matteo Galasso, Cristian Borrazzo and Andrea Fabbri

Do carotid MR surface coils affect PET quantification in PET/MR imaging?

Authors: Martin J Willemink, Mootaz Eldib, Tim Leiner, Zahi A Fayad and Venkatesh Mani

A multi-modal fusion scheme for the enhancement of PET/MR viewing

Authors: Marco Aiello, Serena Monti, Marianna Inglese, Ernest Forte, Carlo Cavaliere, Onofrio Antonio Catalano, Emanuele Nicolai and Marco Salvatore

Simultaneous reconstruction of attenuation and activity for non–TOF PET/MR using MR prior information

Authors: Thorsten Heußer, Christopher M Rank, Thomas Beyer and Marc Kachelrieß

Cross calibration of the Siemens mMR: easily acquired accurate PET phantom measurements, long term stability and reproducibility

Authors: Sune H Keller, Bjorn Jakoby, Adam Espe Hansen, Susanne Svalling and Thomas L Klausen

Tissue probability-based AC for neurological PET/MR using SPM8

Authors: Jarmo Teuho, Jani Linden, Jarkko Johansson, Jouni Tuisku, Terhi Tuokkola and Mika Teras

The SAFIR project: an innovative high rate preclinical PET/MR detector towards dynamic multimodal imaging

Authors: Robert Becker, Chiara Casella, Gunther Dissertori, Jannis Fischer, Alexander Howard, Astrik Jeitler, Werner Lustermann, Ulf Roeser, Qiulin Wang and Bruno Weber

Evaluation of algorithms for photon depth of interaction estimation for the TRIMAGE PET component

Authors: Niccolo Camarlinghi, Nicola Belcari, Piergiorgio Cerello, Giancarlo Sportelli, Francesco Pennazio, Emanuele Zaccario and Alberto Del Guerra

A novel method for γ photons depth of interaction discrimination on monolithic LYSO crystals for brain PET/MRI

Authors: Roberto Pani, Marco Bettiol, Enrico Preziosi, Christian Borrazzo, Rosanna Pellegrini, Antonio Gonzalez, Pablo Conde, Maria Nerina Cinti, Andrea Fabbri, Elisabetta Di Castro and Stan Majewski

Evaluation of a SiPM array detector coupled to a LFS-3 pixellated scintillator for PET/MR applications

Authors: Stratos David, Eleftherios Fysikopoulos, Maria Georgiou and George Loudos

A compact PET detector module using SiPMs and MVT digitizers

Authors: Xiang Liu, Daoming Xi, Chen Zeng, Wei Liu, Rui Chen, Xiongze Mei, Yiexuan Hua, Xiaoyao Feng, Jie Wu, Heejong Kim, Peng Xiao, Chien-Min Kao and Qingguo Xie

3D photon impact determination in monolithic crystals based on autocorrelation filters and RTP methods

Authors: Pablo Conde, Antonio Gonzalez, Marco Bettiol, Andrea Fabbri, Roberto Pani, José María Benlloch Baviera, Albert Talens Aguilar, Liczandro Hernandez and Filomeno Sanchez

SPAD array chips with full frame readout for crystal characterization

Authors: Peter Fischer, Roberto Blanco, Ilaria Sacco, Michael Ritzert and Sascha Weyers

The performance of silicon photomultipliers in Cherenkov TOF PET

Authors: Rok Dolenec, Samo Korpar, Peter Krizan and Rok Pestotink

Performance assessment of a NaI(Tl) gamma counter for PET applications with methods for improved quantitative accuracy and greater standardization

Although NaI(Tl) gamma counters play an important role in many quantitative positron emission tomography (PET) protocols, their calibration for positron-emitting samples has not been standardized across imagin...

Authors: Martin A Lodge, Daniel P Holt, Paul E Kinahan, Dean F Wong and Richard L Wahl

Increased absorbed liver dose in Selective Internal Radiation Therapy (SIRT) correlates with increased sphere-cluster frequency and absorbed dose inhomogeneity

The higher tolerated mean absorbed dose for selective internal radiation therapy (SIRT) with intra-arterially infused ⁹⁰Y microspheres compared to external beam therapy is speculated to be caused by absorbed dose...

Authors: Jonas Högberg, Magnus Rizell, Ragnar Hultborn, Johanna Svensson, Olof Henrikson, Johan Mölne, Peter Gjertsson and Peter Bernhardt

PET image segmentation using a Gaussian mixture model and Markov random fields

Classification algorithms for positron emission tomography (PET) images support computational treatment planning in radiotherapy. Common clinical practice is based on manual delineation and fixed or iterative ...

Authors: Thomas Layer, Matthias Blaickner, Barbara Knäusl, Dietmar Georg, Johannes Neuwirth, Richard P Baum, Christiane Schuchardt, Stefan Wiessalla and Gerald Matz

Dental artifacts in the head and neck region: implications for Dixon-based attenuation correction in PET/MR

In the absence of CT or traditional transmission sources in combined clinical positron emission tomography/magnetic resonance (PET/MR) systems, MR images are used for MR-based attenuation correction (MR-AC). T...

Authors: Claes N Ladefoged, Adam E Hansen, Sune H Keller, Barbara M Fischer, Jacob H Rasmussen, Ian Law, Andreas Kjær, Liselotte Højgaard, Francois Lauze, Thomas Beyer and Flemming L Andersen

Impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion SPECT using cadmium-zinc telluride detectors in the rat

The aims of this study were (1) to evaluate the impact of injection dose, post-reconstruction filtering, and collimator choice on image quality of myocardial perfusion single-photon emission computed tomograph...

Authors: Asuka Mizutani, Ichiro Matsunari, Masato Kobayashi, Kodai Nishi, Wataru Fujita, Yoshiharu Miyazaki, Stephan G Nekolla and Keiichi Kawai

Effects of ferumoxytol on quantitative PET measurements in simultaneous PET/MR whole-body imaging: a pilot study in a baboon model

Simultaneous PET/MR imaging depends on MR-derived attenuation maps (mu-maps) for accurate attenuation correction of PET data. Currently, these maps are derived from gradient-echo-based MR sequences, which are ...

Authors: Ronald JH Borra, Hoon-Sung Cho, Spencer L Bowen, Ulrike Attenberger, Grae Arabasz, Ciprian Catana, Lee Josephson, Bruce R Rosen, Alexander R Guimaraes and Jacob M Hooker

Tumor and red bone marrow dosimetry: comparison of methods for prospective treatment planning in pretargeted radioimmunotherapy

Red bone marrow (RBM) toxicity is dose-limiting in (pretargeted) radioimmunotherapy (RIT). Previous blood-based and two-dimensional (2D) image-based methods have failed to show a clear dose-response relationsh...

Authors: Wietske Woliner-van der Weg, Rafke Schoffelen, Robert F Hobbs, Martin Gotthardt, David M Goldenberg, Robert M Sharkey, Cornelis H Slump, Winette TA van der Graaf, Wim JG Oyen, Otto C Boerman, George Sgouros and Eric P Visser

Clinical evaluation of respiration-induced attenuation uncertainties in pulmonary 3D PET/CT

In contemporary positron emission tomography (PET)/computed tomography (CT) scanners, PET attenuation correction is performed by means of a CT-based attenuation map. Respiratory motion can however induce offse...

Authors: Matthijs F Kruis, Jeroen B van de Kamer, Wouter V Vogel, José SA Belderbos, Jan-Jakob Sonke and Marcel van Herk

Intravenous contrast-enhanced CT can be used for CT-based attenuation correction in clinical ¹¹¹In-octreotide SPECT/CT

CT-based attenuation correction (CT-AC) using contrast-enhancement CT impacts ¹¹¹In-SPECT image quality and quantification. In this study we assessed and evaluated the effect.

Authors: Thomas Levin Klausen, Jann Mortensen, Robin de Nijs, Flemming Littrup Andersen, Liselotte Højgaard, Thomas Beyer and Søren Holm

Evaluation of inter-departmental variability of ejection fraction and cardiac volumes in myocardial perfusion scintigraphy using simulated data

Myocardial perfusion scintigraphy (MPS) is a clinically useful noninvasive imaging modality for diagnosing patients with suspected coronary artery disease. By utilizing gated MPS, the end diastolic volume (EDV...

Authors: Elin Trägårdh, Michael Ljungberg, Lars Edenbrandt, Eva Örndahl, Lena Johansson, Agneta Gustafsson, Cathrine Jonsson, Jessica Hagerman, Katrine Riklund and David Minarik

Development and performance test of an online blood sampling system for determination of the arterial input function in rats

For positron emission tomography (PET) kinetic modelling, an accurate determination of the arterial input function is required. In this study, a blood sampling system was developed and tested using different r...

Authors: Friedrich Roehrbacher, Jens P Bankstahl, Marion Bankstahl, Thomas Wanek, Johann Stanek, Michael Sauberer, Julia Muellauer, Thales Schroettner, Oliver Langer and Claudia Kuntner

The effect of object size on the sensitivity of single photon emission computed tomography: comparison of two CZT cardiac cameras and an Anger scintillation camera

Heart sizes vary greatly across the spectrum of patients referred for myocardial perfusion imaging. We therefore performed a phantom study to explore under controlled circumstances how count rates change when ...

Authors: Elazar A Bienenstock and Marguerite Ennis

Clinical image quality perception and its relation to NECR measurements in PET

The purpose of this study is to describe a clinical relation of noise equivalent count rate (NECR) - an objective measurement of positron emission tomography (PET) systems - measured in a large number of patie...

Authors: Marcelo A Queiroz, Scott D Wollenweber, Gustav von Schulthess, Gaspar Delso and Patrick Veit-Haibach

Metal artifact reduction in patients with dental implants using multispectral three-dimensional data acquisition for hybrid PET/MRI

Hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) shows high potential for patients with oropharyngeal cancer. Dental implants can cause substantial artifacts in the oral cavity impairin...

Authors: Jeanne M Gunzinger, Gaspar Delso, Andreas Boss, Miguel Porto, Helen Davison, Gustav K von Schulthess, Martin Huellner, Paul Stolzmann, Patrick Veit-Haibach and Irene A Burger

Impact of incorrect tissue classification in Dixon-based MR-AC: fat-water tissue inversion

The current MR-based attenuation correction (AC) used in combined PET/MR systems computes a Dixon attenuation map (MR-AC_Dixon) based on fat and water images derived from in- and opposed-phase MRI. We observed an ...

Authors: Claes Nøhr Ladefoged, Adam Espe Hansen, Sune Høgild Keller, Søren Holm, Ian Law, Thomas Beyer, Liselotte Højgaard, Andreas Kjær and Flemming Littrup Andersen