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Table 2 Normalized cumulated activity coefficients (NCAs) for indicated source organs determined from whole-body imaging of three healthy subjects injected intravenously with [11C]-UCB-J

From: Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density

Source organ

NCA (MBq-hr/hr)

Average

Adult female

Adult female

Adult male

Brain

0.0787

0.0633

0.0506

0.0642 ± 0.0141

Gallbladder

0.0030

0.0000

0.0014

0.0015 ± 0.0015

Small intestine

0.0524

0.0341

0.0598

0.0488 ± 0.0133

Right colon

0.0062

0.0041

0.0071

0.0058 ± 0.0015

Left colon

0.0002

0.0001

0.0003

0.0002 ± 0.0001

Stomach

0.0105

0.0047

0.0078

0.0077 ± 0.0029

Heart wall

0.0037

0.0034

0.0053

0.0041 ± 0.0010

Kidneys

0.0144

0.0156

0.0064

0.0121 ± 0.0050

Liver

0.0654

0.0641

0.0705

0.0667 ± 0.0034

Lungs

0.0101

0.0093

0.0121

0.0105 ± 0.0014

Red marrow

0.0211

0.0194

0.0192

0.0199 ± 0.0010

Spleen

0.0015

0.0017

0.0008

0.0013 ± 0.0005

Urinary bladder

0.0358

0.0263

0.0211

0.0277 ± 0.0075

Total body/remainder

0.1720

0.1946

0.1872

0.1846 ± 0.0155