Initial evaluation of a practical PET respiratory motion correction method in clinical simultaneous PET/MRI
© Manber et al; licensee Springer 2014
Published: 29 July 2014
Respiratory motion during PET acquisitions can cause image artefacts, with sharpness and tracer quantification adversely affected due to count ‘smearing’. Motion correction by registration of PET gates becomes increasingly difficult with shorter scan times and less counts. The advent of simultaneous PET/MRI scanners allows the use of high spatial resolution MRI to capture motion states during respiration [1, 2]. In this work, we use a respiratory signal derived from the PET list-mode data [3, 4], with no requirement for an external device or MR sequence modifications.
In the liver case we see a decrease in tumor ‘smearing’ after MRI model-based correction (Figure 3). Other areas of high activity in the liver, only marginally visible in the uncorrected image, become apparent in the motion-corrected image. Average intensity increase over the 3 lesions is 11%, while increase in intensity in the cardiac wall in the cardiac patient is 10%.
Siemens/UCL IMPACT studentship, UK EPSRC (EP/K005278/1) and the NIHR-funded UCH Biomedical Research Centre.
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