GPU-accelerated Monte Carlo based scatter correction in brain PET/MR
© Gaens et al; licensee Springer 2014
Published: 29 July 2014
To develop and evaluate a fast and accurate Monte Carlo simulation (MCS) based scatter correction for PET/MR imaging, based on Geant4 using graphical processing units (GPUs).
The GPU implementation by Bert et al.  including the photon tracking within a voxelized volume was extended with the modeling of the detection process in the Siemens MR-BrainPET. Using NVIDIA’s CUDA photon pairs undergo several kernel functions in parallel, from their generation according to the activity distribution up to their detection in the scanner. Subsequently, coincidences are sorted and stored in list-mode. The new GPU implementation (GeForce GTX690) was validated by comparison with Gate v6.2 on a single CPU (Intel Core i7, 3.4GHz), showing a speedup factor of 135. The use of multiple GPUs can further increase this acceleration.
For Compton scatter correction the reconstructed emission image, the patient MR-derived attenuation map and a CT-derived attenuation template of the MR coils are used as input for the simulation. The resulting simulated projection data are scaled to the normalized measured projection data. Thus, the often unstable fit to the distribution tails, necessary for single scatter simulation (SSS), is circumvented. The scaled simulated scatter distribution is then incorporated in the reconstruction. The proposed scatter correction methodology was evaluated and compared to the SSS approach using sphere phantom measurements. Finally, the effect on patient data was investigated.
Comparison of recovery coefficients after scatter correction based on MCS and SSS. MC-based scatter correction shows improved recovery coefficients for the hot spheres.
Recovery Coefficient [%]
27 mm cold
22 mm cold
17 mm hot
13 mm hot
10 mm hot
8 mm hot
The new GPU-accelerated MCS allows for fast and accurate estimation of scattered coincidences in PET studies using the Siemens MR-BrainPET with a major speed-up compared to standard MCS and superior image quality compared with the standard correction based on SSS.
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