Fig. 6From: Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic modelRelationship between the observed change in PSA and the individually estimated cumulative area under the curve (AUC) in tumors (i.e. time-integrated activity) after the first two treatment cycles, where the change in PSA was determined based on the nadir value (A) and the last measured value (B) compared to the baseline PSA valueBack to article page