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Table 3 Image quality metrics measured by the toolbox before and after harmonization

From: Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan

Quantification metrics

Non-harmonized

Mean ± SD (range)

Harmonized

Mean ± SD (range)

COV%

16.96 ± 6.03 (6–30.55)

7.88 ± 1.49 (5.49–10.64)

GMRC

0.78 ± 0.03 (0.74–0.86)

0.72 ± 0.01 (0.71–0.75)

Contrast

1.82 ± 0.14 (1.55–2.28)

1.54 ± 0.05 (1.44–1.64)

GMRC eroded VOI

0.97 ± 0.03 (0.90–1.04)

0.94 ± 0.02 (0.89–0.98)

Contrast eroded VOI

3.54 ± 0.32 (2.69–4.11)

3.16 ± 0.04 (2.62–3.53)

Left–right hemisphere GM RC ratio

1.02 ± 0.01 (0.99–1.05)

1.02 ± 0.009 (1.00–1.05)

Cold-spot RC

0.04 ± 0.01 (0.01–0.08)

0.05 ± 0.01 (0.02–0.08)