Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan

Shekari, Mahnaz; Verwer, Eline E.; Yaqub, Maqsood; Daamen, Marcel; Buckley, Christopher; Frisoni, Giovanni B.; Visser, Pieter Jelle; Farrar, Gill; Barkhof, Frederik; Gispert, Juan Domingo; Boellaard, Ronald

doi:10.1186/s40658-023-00588-x

EJNMMI Physics

Table 1 Summary of scanner model and image reconstruction settings for each scanner

From: Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan

Manufacturer	S-ID	Model		R-ID	Reconstruction setting					Post-smoothing filter
Manufacturer	S-ID	Model		R-ID	Algorithm	TOF	PSF	I × S	Voxel size (mm³)	FWHM (mm)
GE	1	Discovery MI	PET/CT	1	OSEM	No	No	102	2.00 × 2.00 × 2.79	All-pass
	2	Discovery MI	PET/CT	2	OSEM	No	No	102	2.00 × 2.00 × 2.79	All-pass
	3	Discovery MI	PET/CT	3	OSEM	No	No	96	2.00 × 2.00 × 2.79	All-pass
	4	Discovery MI	PET/CT	4	OSEM	No	No	102	2.00 × 2.00 × 2.79	All-pass
	5	Discovery 690	PET/CT	5	OSEM	No	No	72	1.00 × 1.00 × 3.27	All-pass
	6	Discovery 690	PET/CT	6	OSEM	No	No	180	1.17 × 1.17 × 3.27	All-pass
	6	Discovery 690	PET/CT	7	OSEM	No	No	180	1.17 × 1.17 × 3.27	4.50
Philips	7	Vereos	PET/CT	8	LOR-RAMLA	Yes	No	63	2.00 × 2.00 × 2.00	All-pass
	8	Ingenuity TF	PET/CT	9	BLOB-OS-TF	Yes	No	99	2.00 × 2.00 × 2.00	–
	9	Ingenuity TF	PET/MR	10	LOR-RAMLA	No	No	8	2.00 × 2.00 × 2.00	–
	10	Gemini TF 16	PET/CT	11	LOR-RAMLA	Yes	No	99	2.00 × 2.00 × 2.00	All-pass
Siemens	11	Biograph mCT	PET/CT	12	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	12	Biograph 6 True Point	PET/CT	13	OSEM	No	No	84	1.02 × 1.02 × 2.03	All-pass
	13	Biograph mCT Flow	PET/CT	14	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	14	Biograph 6 True Point	PET/CT	15	OSEM	No	No	64	1.01 × 1.01 × 2.00	All-pass
	15	Biograph 128 mCT	PET/CT	16	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	16	Biograph 6 True Point	PET/CT	17	OSEM	No	No	64	1.01 × 1.01 × 2.00	All-pass
	17	Biograph128 mCT	PET/CT	18	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	18	Biograph mCT Flow	PET/CT	19	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	19	Biograph mCT	PET/CT	20	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	20	Biograph mCT	PET/CT	21	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	21	Biograph mCT	PET/CT	22	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	22	Biograph mCT	PET/CT	23	OSEM	No	No	96	1.02 × 1.02 × 2.03	All-pass
	22	Biograph mCT	PET/CT	24	OSEM	Yes	Yes	168	1.02 × 1.02 × 2.03	3.00
	23	Biograph 40 TruePoint	PET/CT	25	OSEM	No	No	84	1.02 × 1.02 × 2.03	All-pass
	23	Biograph 40 TruePoint	PET/CT	26	OSEM	No	No	84	1.02 × 1.02 × 2.03	4.50
	24	Biograph	PET/MR	27	OSEM	No	No	96	1.04 × 1.04 × 2.03	All-pass
	25	Biograph 2	PET/CT	28	OSEM	No	No	64	1.33 × 1.33 × 3.37	All-pass
	26	Biograph mCT Flow 128 Edge	PET/CT	29	OSEM	Yes	No	96	1.02 × 1.02 × 2.03	All-pass
	27	Biograph mCT Flow 128 Edge	PET/CT	30	OSEM	Yes	No	48	1.59 × 1.59 × 2.00	All-pass
	28	Biograph mMR	PET/MR	31	OSEM	No	No	84	1.40 × 1.40 × 2.03	All-pass

It should be noted that for some scanners, two reconstruction settings were used corresponding to the AMYPAD and historical reconstruction protocols
S-ID system ID, R-ID reconstruction ID, I × S iterations × subsets, OSEM ordered subset expectation maximization, TOF time of flight, PSF point spread function modeling, BLOB-OS spherically symmetric basis function ordered subset algorithm, RAMLA row action maximum likelihood algorithm. System ID nos. 1, 2, and 4 consist of 4 rings with an axial field of view of 198 mm. System no.3 is a GE Discovery MI with 5 rings with an axial field of view of 249 mm

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