A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans

EJNMMI Physics

Table 6 SUVmax of large and small lesions in different scan times and injected dose reconstructed by HYPER Iterative and OSEM

Lesion	Time	Full dose group (n = 10)				Half dose group (n = 10)
Lesion	Time	HYPER Iterative	OSEM	Difference (%)	P	HYPER Iterative	OSEM	Difference (%)	P
SUVmax (large lesion)	10 s	13.93 ± 6.55	14.85 ± 7.10	4.51 ± 6.53	0.074	13.28 ± 3.69	14.73 ± 5.40	4.15 ± 30.48	0.139
	30 s	14.83 ± 5.54	13.94 ± 6.07	8.83 ± 15.03	0.139	14.06 ± 3.96	13.45 ± 4.51	6.99 ± 20.83	0.333
	1 min	14.69 ± 5.76	13.82 ± 6.04	8.07 ± 15.01	0.114	14.22 ± 3.98	13.54 ± 4.69	7.92 ± 20.44	0.203
	2 min	14.65 ± 5.70	13.66 ± 5.76	8.37 ± 11.80	0.017	14.29 ± 3.99	13.32 ± 5.19	12.10 ± 20.79	0.047
	3 min	14.82 ± 5.87	13.75 ± 5.64	8.40 ± 10.57	0.009	14.28 ± 4.11	13.34 ± 5.23	11.77 ± 20.66	0.047
	4 min	14.94 ± 5.94	13.80 ± 5.64	8.76 ± 10.54	0.013	14.39 ± 4.02	13.29 ± 5.01	12.76 ± 20.87	0.047
	5 min	15.08 ± 6.13	13.89 ± 5.83	9.03 ± 10.61	0.013	14.45 ± 4.00	13.27 ± 4.82	12.52 ± 19.20	0.047
SUVmax (Small lesion)	10 s	3.59 ± 1.30	4.73 ± 1.84	10.39 ± 47.25	0.333	3.26 ± 2.09	3.85 ± 2.35	4.84 ± 68.96	0.139
	30 s	4.45 ± 2.82	4.14 ± 1.35	1.82 ± 31.29	0.878	4.47 ± 1.94	3.70 ± 1.89	28.21 ± 36.80	0.139
	1 min	5.12 ± 2.35	4.06 ± 1.36	24.19 ± 28.95	0.028	5.86 ± 1.90	3.86 ± 1.91	61.46 ± 29.27	0.005
	2 min	5.57 ± 2.45	4.13 ± 1.53	33.30 ± 22.22	0.007	5.89 ± 1.61	3.75 ± 1.87	71.70 ± 46.61	0.005
	3 min	5.77 ± 2.74	4.19 ± 1.69	36.11 ± 20.51	0.005	5.98 ± 1.59	3.78 ± 1.89	73.96 ± 47.79	0.005
	4 min	6.16 ± 2.79	4.29 ± 1.81	44.17 ± 20.94	0.005	5.96 ± 1.59	3.79 ± 1.95	74.27 ± 47.42	0.005
	5 min	6.18 ± 2.99	4.29 ± 1.94	45.21 ± 22.57	0.005	5.99 ± 1.64	3.81 ± 1.99	74.96 ± 48.77	0.005