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Table 5 SUVmax of radioactivity distribution in homogeneous background in the liver and blood pool in different scan times and injected dose reconstructed by HYPER Iterative and OSEM

From: A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans

Viscera

Time

Full dose group (n = 10)

Half dose group (n = 10)

HYPER Iterative

OSEM

Difference (%)

P

HYPER Iterative

OSEM

Difference (%)

P

Liver SUVmax

10 s

3.07 ± 0.44

3.91 ± 0.66

28.43 ± 20.45

0.005

2.78 ± 0.88

4.26 ± 2.31

49.68 ± 38.73

0.005

30 s

2.79 ± 0.42

3.21 ± 0.42

15.47 ± 6.42

0.005

2.67 ± 0.58

3.18 ± 0.78

18.53 ± 9.18

0.005

1 min

2.75 ± 0.44

2.90 ± 0.49

5.32 ± 2.76

0.007

2.50 ± 0.62

2.85 ± 0.80

13.39 ± 5.13

0.005

2 min

2.67 ± 0.38

2.77 ± 0.38

4.07 ± 1.50

0.005

2.41 ± 0.55

2.60 ± 0.62

7.66 ± 2.41

0.005

3 min

2.64 ± 0.36

2.72 ± 0.37

3.08 ± 1.42

0.005

2.36 ± 0.54

2.50 ± 0.58

6.21 ± 0.81

0.005

4 min

2.68 ± 0.35

2.73 ± 0.37

1.99 ± 1.32

0.009

2.35 ± 0.54

2.47 ± 0.59

4.98 ± 1.94

0.005

5 min

2.60 ± 0.31

2.64 ± 0.33

1.33 ± 1.29

0.017

2.31 ± 0.52

2.40 ± 0.56

3.74 ± 1.73

0.005

Blood pool SUVmax

10 s

2.34 ± 0.45

3.14 ± 0.89

33.97 ± 24.03

0.005

2.23 ± 0.50

3.18 ± 0.86

42.01 ± 19.67

0.005

30 s

2.14 ± 0.42

2.62 ± 0.54

23.12 ± 16.11

0.005

2.00 ± 0.42

2.49 ± 0.61

25.94 ± 23.79

0.005

1 min

2.00 ± 0.26

2.37 ± 0.35

18.78 ± 13.34

0.005

1.96 ± 0.48

2.29 ± 0.45

20.19 ± 26.34

0.005

2 min

1.97 ± 0.29

2.06 ± 0.35

4.43 ± 3.71

0.005

1.89 ± 0.49

2.03 ± 0.53

7.50 ± 3.13

0.005

3 min

1.91 ± 0.26

1.99 ± 0.28

3.75 ± 2.71

0.005

1.84 ± 0.48

1.95 ± 0.52

5.77 ± 3.75

0.005

4 min

1.89 ± 0.23

1.94 ± 0.25

2.67 ± 2.45

0.007

1.83 ± 0.49

1.92 ± 0.54

4.22 ± 2.70

0.005

5 min

1.87 ± 0.20

1.91 ± 0.20

2.19 ± 1.84

0.013

1.84 ± 0.51

1.90 ± 0.53

3.08 ± 1.59

0.005