A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans

EJNMMI Physics

Table 4 SD of radioactivity distribution in homogeneous background in the liver and blood pool in different scan times and injected dose reconstructed by HYPER iterative and OSEM

Homogeneous background	Time	Full dose group (n = 10)				Half dose group (n = 10)
Homogeneous background	Time	HYPER Iterative	OSEM	SD_OSEM/SD_HYPER	P	HYPER Iterative	OSEM	SD_OSEM/SD_HYPER	P
Liver SD	10 s	0.11 ± 0.08	0.49 ± 0.38	3.50 ± 2.05	0.005	0.13 ± 0.11	1.17 ± 1.65	8.29 ± 7.00	0.005
	30 s	0.04 ± 0.04	0.11 ± 0.07	2.45 ± 1.51	0.005	0.06 ± 0.04	0.25 ± 0.13	3.48 ± 1.66	0.005
	1 min	0.02 ± 0.02	0.05 ± 0.03	1.40 ± 0.71	0.005	0.05 ± 0.03	0.14 ± 0.10	2.34 ± 1.37	0.005
	2 min	0.02 ± 0.01	0.04 ± 0.02	1.09 ± 0.47	0.005	0.02 ± 0.01	0.07 ± 0.03	1.95 ± 0.53	0.005
	3 min	0.02 ± 0.01	0.03 ± 0.02	0.87 ± 0.55	0.005	0.01 ± 0.01	0.03 ± 0.02	1.24 ± 0.54	0.005
	4 min	0.02 ± 0.01	0.03 ± 0.02	0.42 ± 0.34	0.007	0.01 ± 0.01	0.03 ± 0.01	1.03 ± 0.83	0.005
	5 min	0.01 ± 0.01	0.02 ± 0.01	0.29 ± 0.28	0.022	0.01 ± 0.01	0.02 ± 0.02	0.97 ± 0.54	0.005
Blood pool SD	10 s	0.07 ± 0.04	0.35 ± 0.20	4.84 ± 3.26	0.005	0.11 ± 0.06	0.54 ± 0.34	4.90 ± 1.67	0.005
	30 s	0.04 ± 0.05	0.14 ± 0.13	2.38 ± 1.20	0.005	0.04 ± 0.02	0.13 ± 0.07	2.52 ± 1.08	0.005
	1 min	0.03 ± 0.01	0.07 ± 0.03	1.32 ± 0.56	0.005	0.03 ± 0.02	0.09 ± 0.06	1.62 ± 1.00	0.005
	2 min	0.02 ± 0.02	0.04 ± 0.03	0.95 ± 0.41	0.005	0.02 ± 0.02	0.05 ± 0.03	1.48 ± 0.69	0.005
	3 min	0.01 ± 0.01	0.02 ± 0.02	0.92 ± 0.60	0.005	0.02 ± 0.01	0.04 ± 0.02	1.16 ± 0.45	0.005
	4 min	0.01 ± 0.01	0.02 ± 0.01	0.74 ± 0.50	0.005	0.02 ± 0.01	0.03 ± 0.02	0.91 ± 0.39	0.005
	5 min	0.01 ± 0.01	0.01 ± 0.01	0.74 ± 0.51	0.005	0.02 ± 0.01	0.03 ± 0.02	0.60 ± 0.20	0.005