Table 2 Intercellular cross-dose S-values (GyBq−1 s−1) for radionuclides in the 225Ac decay chain from different source distributions targeting the cell nucleus of a neighbouring cell
From: A GATE simulation study for dosimetry in cancer cell and micrometastasis from the 225Ac decay chain
Radionuclide | S-value (GyBq−1 s−1) | |||
|---|---|---|---|---|
Cell surface | Cytoplasm | Nucleus | Whole cell | |
225Ac | 1.29 × 10–2 (− 1.8%) | 1.21 × 10–2 (− 5.3%) | 1.10 × 10–2 (− 9.7%) | 1.19 × 10–2 (− 4.9%) |
221Fr | 1.21 × 10–2 (− 0.3%) | 1.16 × 10–2 (− 1.9%) | 1.04 × 10–2 (− 7.3%) | 1.02 × 10–2 (− 10.9%) |
217At | 1.01 × 10–2 (− 7.9%) | 1.00 × 10–2 (− 6.3%) | 9.70 × 10–3 (− 5.8%) | 9.37 × 10–3 (− 10.7%) |
213Bi | 3.34 × 10–4 (3.5%) | 2.75 × 10–4 (− 12.7%) | 2.77 × 10–4 (− 7.5%) | 2.84 × 10–4 (− 7.5%) |
213Po | 9.38 × 10–3 (− 1.5%) | 8.91 × 10–3 (− 4.2%) | 8.23 × 10–3 (− 6.7%) | 8.25 × 10–3 (− 8.9%) |
209Tl | 4.66 × 10–5 (− 44.3%) | 4.29 × 10–5 (− 46.8%) | 4.47 × 10–5 (− 40.1%) | 4.43 × 10–5 (− 44.6%) |
209Pb | 6.27 × 10–5 (8.3%) | 6.07 × 10–5 (7.8%) | 5.72 × 10–5 (8.0%) | 5.77 × 10–5 (5.7%) |
Total | 4.46 × 10–2 (− 2.7%) | 4.28 × 10–2 (− 4.5%) | 3.95 × 10–2 (− 7.5%) | 3.99 × 10–2 (− 8.7%) |