Development of a bespoke phantom to optimize molecular PET imaging of pituitary tumors

EJNMMI Physics

Table 3 Results of image evaluation

Reconstruction	Confusion matrix			Confidence				Combined
Reconstruction	Sensitivity	Specificity	Accuracy	True positive confidence	True negative confidence	False positive confidence	True negative confidence	Summed confidence
OSEM 128 TOF 3i24s	62	95	83	1.86	2.86	− 0.25	− 1.59	30.8
OSEM 128 TOF PSF 3i24s	78	90	89	2.78	2.32	− 0.88	− 0.44	37.1
OSEM 256 TOF PSF 3i24s	78	90	88	3.02	2.51	− 1.38	− 1.22	39.1
OSEM 256 TOF PSF 5i24s	81	79	84	3.09	2.30	− 1.47	− 2.67	34.4
OSEM 256 TOF PSF 7i24s	84	60	74	3.01	1.98	− 0.84	− 1.00	30.1
OSEM 256 TOF PSF 9i25s	86	56	73	2.94	2.04	− 0.94	− 1.00	29.1
BPL 256 TOF PSF β50	86	32	60	3.03	1.31	− 1.18	− 4.00	19.2
BPL 256 TOF PSF β100	89	47	70	3.14	1.79	− 1.12	0.00	27.3
BPL 256 TOF PSF β200	86	74	84	3.16	2.24	− 0.95	0.00	37.3
BPL 256 TOF PSF β300	83	84	88	3.07	2.52	− 1.54	0.00	39.7
BPL 256 TOF PSF β400	77	93	90	2.98	2.51	− 1.33	− 0.90	39.6
BPL 256 TOF PSF β500	68	95	86	3.02	2.86	− 0.25	− 1.65	39.7
BPL 256 TOF PSF β600	68	95	86	2.93	2.77	− 1.25	− 1.76	37.7
BPL 256 TOF PSF β800	67	95	86	2.83	2.82	− 1.00	− 1.72	37.3
BPL 256 TOF PSF β1000	64	95	86	2.71	2.86	− 1.00	− 1.75	37.1