Table 2 Parameters estimated from ATP fitting using the best model obtained from the best function derived using MS–NLME method, i.e. \(f_{4d}\)
Model parameters | Fixed effect (% coefficient of variation) | Random effect (variance, inter-patient variability) |
|---|---|---|
\(A\) | 129.36 (10.5) min | 0.08 |
\(\alpha\) | 0.31 (7.6) | 0.01 |
\(\lambda_{1}\)a | 1.5 × 10–4 (9.8)/min | 2.9 × 10−4 |
\(\lambda_{2}\)b | 8.8 × 10–4 (41.4)/min | 1.1 |
Intra-patient variability | 4.4 × 10–2 (21) | – |