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Table 3 Comparison of the performance parameters to quantitative methodsConcordance Correlation Coefficients (CCC) for the evaluation of the accuracy of each semiquantitative method, linear regression coefficients, Pearson coefficients (\(\rho\)) and Coefficient of Determination (\(\rho ^{\textrm{2}}\))

From: Assessment of different regions of interest-based methods for [99mTc]Tc DAT-SPECT quantification using an anthropomorphic striatal phantom

Method

Index measured\(^{1}\)

Concordance correlation coefficient-CCC

Coefficients of linear regression analysis\(^{2}\)

High

Intermediary

Low

(10:1 to 8:1)

(7:1 to 6:1)

(4:1 to 2:1)

Intercept (CI)

SE

          Slope (CI)                 

SE

\(\rho\)

\(\rho ^{\textrm{2}}\)

Manual

 

\(\hbox {BPI}_{\textrm{CA}}\)

0.021 (0.003 ; 0.039)

0.028 (0.007 ; 0.049)

0.095 (0.011 ; 0.177)

-0.435(-0.692;-0.178)

0.127

0.417 (0.38;0.452)

0.017

0.964

0.929

 

\(\hbox {BPI}_{\textrm{PU}}\)

0.017 (-0.001 ; 0.035)

0.034 (0.009 ; 0.059)

0.096 (0.013 ; 0.177)

-0.504 (-0.789;-0.219)

0.141

0.414 (0.375;0.453)

0.019

0.959

0.913

 

\(\hbox {BPI}_{\textrm{ST}}\)

0.013 (0.000 ; 0.026)

0.026 (0.007 ; 0.046)

0.081 (0.010 ; 0.152)

-0.457 (-0.700;-0.210)

0.121

0.38 (0.346;0.413)

0.016

0.961

0.923

MRI

 

\(\hbox {BPI}_{\textrm{CA}}\)

0.235 (0.072 ; 0.386)

0.255 (0.099 ; 0.399)

0.495 (0.221 ; 0.697)

-0.464(-0.885;-0.043)

0.208

0.804(0.747;0.861)

0.028

0.974

0.947

 

\(\hbox {BPI}_{\textrm{PU}}\)

0.243 (0.073 ; 0.398)

0.265 (0.106 ; 0.411)

0.456 (0.189 ; 0.661)

-0.722(-1.164;-0.28)

0.219

0.835(0.775;0.895)

0.029

0.973

0.946

 

\(\hbox {BPI}_{\textrm{ST}}\)

0.239 (0.074 ; 0.391)

0.261 (0.104 ; 0.405)

0.473 (0.203 ; 0.677)

-0.608(-1.033;-0.182)

0.211

0.821(0.763;0.879)

0.028

0.974

0.949

CT

 

\(\hbox {BPI}_{\textrm{CA}}\)

0.239 (0.072 ; 0.392)

0.244 (0.093 ; 0.383)

0.438 (0.177 ; 0.642)

-0.766(-1.21;-0.322)

0.22

0.835(0.775;0.896)

0.029

0.973

0.946

 

\(\hbox {BPI}_{\textrm{PU}}\)

0.226 (0.065 ; 0.376)

0.252 (0.100 ; 0.393)

0.421(0.163 ; 0.625)

-0.878(-1.326;-0.43)

0.222

0.843(0.782;0.903)

0.03

0.973

0.946

 

\(\hbox {BPI}_{\textrm{ST}}\)

0.233 (0.071 ; 0.383)

0.248 (0.097 ; 0.388)

0.428 (0.169 ; 0.632)

-0.828(-1266;-0.391)

0.217

0.839(0.78;0.899)

0.029

0.974

0.948

TwoBox

 

SBR

0.535 (0.242 ; 0.738)

0.497 (0.241 ; 0.688)

0.750 (0.488 ; 0.888)

-0.293(-0.8;0.213)

0.251

0.902(0.833;0.971)

0.034

0.969

0.94

ThreeBox

 

TBPI

0.002(0.000 ; 0.004)

0.005(0.004 ; 0.008)

0.027 (0.002 ; 0.053)

-4.467(-5.303;-3.633)

0.41

0.114(1.31;1.552)

0.056

0.972

0.944

  1. \(^{1}\) The indexes are represented through of the quality parameter and confidence interval.
  2. \(^{2}\) The coefficients are represented with the confidence interval (CI) and standard error(SE)