Exploration of the total-body PET/CT reconstruction protocol with ultra-low 18F-FDG activity over a wide range of patient body mass indices

EJNMMI Physics

Table 2 Image quality using different reconstruction parameters

Reconstructions	Underweight (n = 12)		Normal (n = 20)		Overweight (n = 20)		Obese (n = 11)
Reconstructions	SNR	Noise	SNR	Noise	SNR	Noise	SNR	Noise
OSEM3	19.8 ± 4.9	0.11 ± 0.03	16.8 ± 2.7	0.17 ± 0.04	15.0 ± 2.2	0.18 ± 0.02	12.7 ± 1.7	0.23 ± 0.04
OSEM2	27.5 ± 8.1**	0.08 ± 0.02**	23.1 ± 3.9**	0.12 ± 0.03**	21.0 ± 2.9**	0.13 ± 0.02**	18.1 ± 2.1	0.16 ± 0.03
HYPER0.3	19.1 ± 5.9	0.12 ± 0.03	19.7 ± 2.7	0.14 ± 0.03**	19.5 ± 3.2	0.14 ± 0.02**	18.6 ± 2.1	0.16 ± 0.03
HYPER0.4	22.0 ± 6.7	0.10 ± 0.02	23.0 ± 3.2**	0.12 ± 0.02**	23.0 ± 3.8**	0.12 ± 0.02**	21.9 ± 2.6**	0.13 ± 0.02**
HYPER0.5	24.7 ± 7.6*	0.09 ± 0.02	26.4 ± 4.0**	0.11 ± 0.02**	26.1 ± 4.5**	0.11 ± 0.02**	25.4 ± 3.0**	0.11 ± 0.02**
HYPER0.6	27.5 ± 8.5**	0.08 ± 0.02**	29.4 ± 4.6**	0.10 ± 0.02**	29.3 ± 5.2**	0.09 ± 0.02**	28.7 ± 3.2**	0.10 ± 0.02**