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Table 1 Acquisition settings of single SPECT scans performed in experiment 1 on 14 mice injected with the [131I]-labelled sdAb (dataset SS1), used for the comparison of kidney activity against gamma counting

From: Assessment of mouse-specific pharmacokinetics in kidneys based on 131I activity measurements using micro-SPECT

Av. time p.i. to death [max. range of variation between mice] (h)

Animal setting

No of mice, n

No of bed positions per scan

Scan time per bed position (s)

Total effective scan time (min)

1.5 [± 0.0]

Post-mortem

3

20

66

22

6.6 [± 0.0]

Post-mortem

3

20

66

22

24.3§ [± 0.8]

In vivo

5

20

225

75

73.4* [± 2.0]

In vivo

3

20

239

80

  1. §23.6 h average time p.i. to middle of scan
  2. *72.6 h average time p.i. to middle of scan