Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium–zinc–telluride-based SPECT/CT system: a phantom study

Zhang, Ruyi; Wang, Miao; Zhou, Yaqian; Wang, Shen; Shen, Yiming; Li, Ning; Wang, Peng; Tan, Jian; Meng, Zhaowei; Jia, Qiang

doi:10.1186/s40658-021-00412-4

EJNMMI Physics

Table 1 Correlation and linear regression analysis of RCs among different acquisition and reconstruction parameters

From: Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium–zinc–telluride-based SPECT/CT system: a phantom study

			37 mm	28 mm	22 mm	17 mm	13 mm	10 mm
32:1	Iterations (1–35)	Regression coefficient	0.63	0.93	0.93	1.21	1.60	1.47
		r	0.58	0.62*	0.70*	0.80*	0.90**	0.92**
	Iterations (35–90)	Regression coefficient	0.02	0.03	0.03	0.04	0.11	0.15
		r	0.98**	0.99**	0.99**	0.97**	0.97**	0.99**
	Subsets	Regression coefficient	0.09	0.15	0.20	0.39	0.69	0.70
		r	0.68	0.80*	0.87*	0.89*	0.84*	0.85*
	FWHM	Regression coefficient	− 11.36	− 11.83	− 9.96	− 10.28	− 10.88	− 9.49
		r	− 1.00**	− 0.99**	− 0.98**	− 0.96**	− 0.92*	− 0.87*
	Acquisition time (s/frame)	Regression coefficient	− 0.01	0.04	0.07	0.05	0.05	0.05
		r	− 0.62	0.84*	0.72*	0.66	0.36	0.36
16:1	Iterations (1–35)	Regression coefficient	0.70	1.04	1.03	1.37	1.28	1.59
		r	0.59	0.66*	0.74*	0.84*	0.92**	0.95**
	Iterations (35–90)	Regression coefficient	0.02	0.03	0.03	0.04	0.11	0.15
		r	0.98**	0.98**	0.98**	0.98**	0.98**	0.98**
	Subsets	Regression coefficient	0.07	0.12	0.13	0.35	0.69	1.14
		r	0.61	0.64	0.70	0.76*	0.86*	0.90*
	FWHM	Regression coefficient	− 11.02	− 11.83	− 9.85	− 10.65	− 8.68	− 10.09
		r	− 1.00**	− 0.99**	− 0.99**	− 0.96**	− 0.92*	− 0.86*
	Acquisition time (s/frame)	Regression coefficient	− 0.04	− 0.03	− 0.02	− 0.04	0.02	0.28
		r	− 0.63	− 0.55	− 0.73*	− 0.68	0.29	0.82*
8:1	Iterations (1–35)	Regression coefficient	0.80	1.15	1.15	1.23	1.29	0.98
		r	0.63*	0.72*	0.82*	0.88**	0.95**	0.94**
	Iterations (35–90)	Regression coefficient	0.02	0.04	0.03	0.06	0.17	0.06
		r	0.98**	0.99**	0.98**	0.98**	0.98**	0.94**
	Subsets	Regression coefficient	0.08	0.10	0.26	0.47	0.90	0.40
		r	0.65	0.52	0.83*	0.85*	0.83*	0.66
	FWHM	Regression coefficient	− 9.95	− 10.90	− 8.73	− 8.79	− 9.22	− 6.23
		r	− 1.00**	− 0.99**	− 0.98**	− 0.96**	− 0.92*	− 0.90*
	Acquisition time (s/frame)	Regression coefficient	0.09	0.04	− 0.02	0.01	0.12	− 0.31
		r	0.70	0.62	− 0.44	0.02	0.43	− 0.71*
4:1	Iterations (1–35)	Regression coefficient	0.87	1.26	1.10	1.09	0.51	0.81
		r	0.69*	0.81*	0.85**	0.92**	0.96**	0.95**
	Iterations (35–90)	Regression coefficient	0.02	0.05	0.03	0.07	0.12	0.19
		r	0.98**	0.98**	0.97**	0.96**	0.99**	0.99**
	Subsets	Regression coefficient	− 0.06	0.11	0.16	0.50	0.56	1.14
		r	− 0.34	0.44	0.57	0.76*	0.87*	0.98**
	FWHM	Regression coefficient	− 8.59	− 9.39	− 7.24	− 7.51	− 4.23	− 6.10
		r	− 1.00**	− 0.99**	− 0.99**	− 0.96**	− 0.90*	− 0.89*
	Acquisition time (s/frame)	Regression coefficient	0.16	0.21	− 0.08	0.24	0.26	− 0.34
		r	0.71*	0.76*	− 0.68	0.82*	0.70	− 0.53

**, P-value < 0.001; *, P-value < 0.05; r, Pearson r

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