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Table 2 Effect of examined parameters on ACrec, HSRC and SNR. The results are exemplified for the largest sphere volume in comparison to a reference protocola.

From: Optimization of SPECT/CT imaging protocols for quantitative and qualitative 99mTc SPECT

Parameter of variation ΔACrec pb ΔHSRC pb ΔSNR pb
(kBq/ml)
SCF: 0.41 + 6.7 < 0.0001 + 0.08 < 0.0001 + 1.1 n.s.d
Iteration set: 4i/10s + 4.1 < 0.0001 + 0.05 < 0.0001 − 8.2 < 0.0001
Iteration set: 5i/15s + 5.6 < 0.0001 + 0.07 < 0.0001 − 11.9 < 0.0001
Iteration set: 24i/10s + 6.6 < 0.0001 + 0.08 < 0.0001 − 17.9 < 0.0001
Acquisition: NEMAc − 0.9 0.04 − 0.01 0.04 + 0.6 n.s.d
  1. Analysis performed for the largest sphere. For residual spheres see supplementary Table 1.
  2. aClinical standard for diagnostic imaging and reconstruction (60 projections with 20 s/projection, SCF1.10, 2i/10s, Butterworth postfilter)
  3. bANOVA post hoc test
  4. cNEMA acquisition protocol (120 projections and 10 s/projection)
  5. dNot significant, tested by ANOVA
  6. SCF scatter weighting factor, ACrec mean reconstructed activity concentration, HSRC hot spot recovery coefficient, SNR signal-to-noise ratio