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Table 1 Average residence time and standard deviation calculated using spline method and multi-exponential methods

From: Internal dosimetry in F-18 FDG PET examinations based on long-time-measured organ activities using total-body PET/CT: does it make any difference from a short-time measurement?

Organ Spline method Multi-exponential method 12 frames Multi-exponential method 12 frames (only physical decay after 60 min) Multi-exponential method 3 frames Multi-exponential method 3 frames (only physical decay after 70 min) Multi-exponential with 18 min of data
Brain 0.391±0.066 0.377±0.073* 0.358±0.071** 0.380±0.067* 0.354±0.065*** 0.370±0.073**
Heart 0.041±0.022 0.044±0.021 0.039±0.019 0.040±0.023 0.036±0.018 0.044±0.038
Liver 0.117±0.025 0.099±0.015*** 0.136±0.021*** 0.086±0.013*** 0.135±0.021*** 0.101±0.023*
Lungs 0.058±0.030 0.062±0.038 0.071±0.038*** 0.049±0.022 0.072±0.032** 0.057±0.030
Kidneys 0.033±0.009 0.032±0.011 0.041±0.012*** 0.025±0.008*** 0.040±0.013*** 0.028±0.033*
  1. Data are mean ± standard deviation for each study
  2. *Significant at 10% level
  3. **Significant at 5% level
  4. ***Significant at 1% level