Can a penalized-likelihood estimation algorithm be used to reduce the injected dose or the acquisition time in 68Ga-DOTATATE PET/CT studies?

Chicheportiche, Alexandre; Goshen, Elinor; Godefroy, Jeremy; Grozinsky-Glasberg, Simona; Oleinikov, Kira; Meirovitz, Amichay; Gross, David J.; Ben-Haim, Simona

doi:10.1186/s40658-021-00359-6

EJNMMI Physics

Table 1 Demographic data and patient characteristics

From: Can a penalized-likelihood estimation algorithm be used to reduce the injected dose or the acquisition time in ⁶⁸Ga-DOTATATE PET/CT studies?

Pt no.	Age (years)	Body weight (kg)	Dose (MBq)	Uptake time (min)	Primary tumor	Primary tumor site	Sites of metastases
1	78	59	170.2	74	Small bowel NET	Resected	Liver, LN above and below the diaphragm
2	73	100	155.4	69	Pheochromocytoma	Local recurrence in right adrenal bed	Retroperitoneal LN, omentum
3	68	97	199.8	58	Lung NET	Resected	Mediastinal LN, bones
4	46	71	188.7	61	Pancreatic NET	Pancreas	Mesenteric, retroperitoneal LN, liver, bones
5	28	70	144.3	76	Pancreatic NET	Pancreas	(nonconclusive bone focus, resolved on FUP)
6	11	43	155.4	62	Lung carcinoid	Lung mass	Mediastinal LN
7	64	53	133.2	76	Pancreatic NET	Local recurrence in surgical bed	Liver, Liver hilum LN, bones
8	66	68	159.1	70	Lung NET	Lung several foci	Mediastinal and right hilar LN
9	60	59	159.1	54	Glucagonoma	Local recurrence in surgical bed	Mesenteric LN, mediastinal LN, bones
10	83	65	159.1	81	Pancreatic NET	Pancreas	Right iliac crest and mediastinal LN
11	79	60	159.1	57	Unknown origin	Unknown	Liver, bone
12	27	53	173.9	62	Bronchial carcinoid	Resected	Bones, soft tissue
13	49	65	122.1	65	Pancreatic NET	Pancreas	Liver
14	66	59	136.9	74	Pancreatic NET	Resected , local recurrence	Liver
15	67	75	162.8	74	Small bowel NET	Resected	Pancreas, liver
16	70	119	203.5	63	Appendiceal carcinoid	Resected	Liver
17	71	59	148	78	Pancreatic NET	Pancreas	Liver
18	73	110	247.9	79	Pancreatic NET	Pancreas	N/A
19	13	40	129.5	53	Insulinoma	Pancreas	Liver, retroperitoneal LN
20	38	83	111.0	88	Pancreatic NET	Pancreas	LN above and below the diaphragm
21	75	72	122.1	91	Lung NET	Lung	Brain
22	72	88	140.6	58	Small bowel NET	Resected	Liver, omentum
23	59	46	166.5	61	Small bowel NET	Resected	Liver hilum LN
24	56	71	103.6	73	Pancreatic NET	Resected	Liver, bones
25	38	65	162.7	72	Lung NET	Lung	N/A
26	60	63	185	57	Small bowel NET	Resected	Liver
27	65	80	144.3	78	Medullary Thyroid Ca	Left lobe resected	Surgical bed
28	42	72	148.2	59	Small bowel NET	Resected	Liver, mesenteric LN
29	74	66	185.0	69	Paraganglioma	Resected	Local recurrence (brain), bone
30	70	84	233.1	58	Unknown origin	Unknown	Bones, right hilum
Mean ± SD	58 ± 19	71 ± 18	160.3 ± 32.0	68 ± 10	–	–	–

NET neuroendocrine tumor, LN lymph node, FUP follow-up plan

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