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EJNMMI Physics
Fig. 5 | EJNMMI Physics

Fig. 5

From: Explicit measurement of multi-tracer arterial input function for PET imaging using blood sampling spectroscopy

Fig. 5

Kinetic compartment models for 68Ga-DOTA (a) and 18FDG (b). The model for 68Ga-DOTA is a single-tissue compartment model as the radiotracer diffuses bidirectionally between the intravascular space and extravascular extracellular space (interstitial space). The model for 18FDG is an irreversible two-tissue compartment model as the radiotracer diffuses bidirectionally between the intravascular and cellular space, and once it enters the myocyte, it can phosphorylate to 18FDG-6-phosphate and remains trapped as it cannot be further metabolized

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