Skip to main content

Table 3 Comparison between the doses delivered by Golgi to nucleus for 2 geometrical assumptions: PM models and simplified CSG. The data are listed in increasing order of Golgi volume (Vg)

From: Cellular dosimetry of [177Lu]Lu-DOTA-[Tyr3]octreotate radionuclide therapy: the impact of modeling assumptions on the correlation with in vitro cytotoxicity

PM

Vg (μm3)

S(N ← G)

\( \left[\frac{\mathrm{Gy}}{\mathrm{Bq}\ \mathrm{s}}\right] \)

CSG

Vg (μm3)

S(N ← G)

\( \left[\frac{\mathrm{Gy}}{\mathrm{Bq}\ \mathrm{s}}\right] \)

123

1.05E−04

110

3.67E−05

80

8.71E−05

94

3.70E−05

68

1.05E−04

86

3.75E−05

63

1.32E−04

78

3.60E−05

60

8.57E−05

70

4.40E−05

54

8.12E−05

62

4.78E−05

31

6.96E−05

54

6.32E−05

25

5.41E−05

46

6.71E−05

24

1.22E−04

38

8.87E−05

Average

(9.4±2.5) E−05

Average

(5.1±1.8) E−05

  1. Cell volumes: 1900 ÷ 5500 μm3 and nucleus volumes: 570 ÷ 1652 μm3, corresponding to reference MIRD cell with Rc = 8 ÷ 11 μm and Rn = 6 ÷ 7 μm