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Table 6 Radiation dosimetry estimates per unit administered activity [μGy/MBq] from IDAC-dose 2.1 for free 211At and 211At-MABG for human adult male phantom. It was calculated by extrapolation from the distribution data of mice

From: Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Target organs 211At-Free 211At-MABG
Adrenal gland 116.00 517.00
Brain 20.20 6.80
Esophagus 21.90 6.50
Eye lenses 0.14 0.08
Gallbladder wall 4.79 1.94
Left colon wall 110.00 135.00
Small intestine wall 170.00 195.00
Stomach wall 667.00 211.00
Right colon wall 110.00 135.00
Recto-sigmoid colon wall 23.40 6.68
Heart wall 150.00 443.00
Kidney 131.00 115.00
Liver 85.70 137.00
Lung 31.10 9.24
Pancreas 110.00 92.40
Prostate 4.47 1.38
Salivary gland 758.00 438.00
Red (active) bone marrow 32.80 9.68
Endosteum (bone surface) 22.80 9.91
Spleen 266.00 182.00
Testis 241.00 67.80
Thymus 4.84 1.59
Thyroid 4160.00 1140.00
Urinary bladder wall 2.42 0.85