Table 6 Radiation dosimetry estimates per unit administered activity [μGy/MBq] from IDAC-dose 2.1 for free 211At and 211At-MABG for human adult male phantom. It was calculated by extrapolation from the distribution data of mice
Target organs | 211At-Free | 211At-MABG |
|---|---|---|
Adrenal gland | 116.00 | 517.00 |
Brain | 20.20 | 6.80 |
Esophagus | 21.90 | 6.50 |
Eye lenses | 0.14 | 0.08 |
Gallbladder wall | 4.79 | 1.94 |
Left colon wall | 110.00 | 135.00 |
Small intestine wall | 170.00 | 195.00 |
Stomach wall | 667.00 | 211.00 |
Right colon wall | 110.00 | 135.00 |
Recto-sigmoid colon wall | 23.40 | 6.68 |
Heart wall | 150.00 | 443.00 |
Kidney | 131.00 | 115.00 |
Liver | 85.70 | 137.00 |
Lung | 31.10 | 9.24 |
Pancreas | 110.00 | 92.40 |
Prostate | 4.47 | 1.38 |
Salivary gland | 758.00 | 438.00 |
Red (active) bone marrow | 32.80 | 9.68 |
Endosteum (bone surface) | 22.80 | 9.91 |
Spleen | 266.00 | 182.00 |
Testis | 241.00 | 67.80 |
Thymus | 4.84 | 1.59 |
Thyroid | 4160.00 | 1140.00 |
Urinary bladder wall | 2.42 | 0.85 |