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Table 4 Radiation dosimetry estimates per unit administered activity [Gy/MBq] for free 211At and 211At-MABG for 25 g mouse phantom in OLINDA/EXM ver. 2.0, based on mouse biodistribution data

From: Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Target organ

211At-Free

211At-MABG

Brain

0.037

0.012

Large intestine

0.240

0.263

Small intestine

0.336

0.348

Stomach wall

5.370

1.600

Heart

0.218

0.099

Kidney

0.518

0.463

Liver

0.153

0.317

Lung

1.910

0.994

Pancreas

0.145

0.138

Skeleton

0.094

0.065

Spleen

0.652

0.405

Testis

0.372

0.107

Thyroid

15.100

4.080

Urinary bladder

0.094

0.065

Total body

0.189

0.145