Fig. 1.

A schematic cross-sectional view of the models considered for distribution of GNPs in the cell. a Gold-tissue mixture. b Homogeneously distributed GNPs in the medium. c Heterogeneous model, with GNPs distributed inside the cytoplasm surrounding the nucleus. In the mixture model, the medium is filled with a homogeneous mixture of eye melanoma and gold. In all three models, the medium is a cubic box of 50 × 50 × 50 μm³, and the nucleus is filled with water