Table 1 OSS for joint kidney and tumour dosimetry based on the hybrid planar/SPECT method and on the approximation by Hänscheid et al. [13] (Eq. 4)
From: Influence of sampling schedules on [177Lu]Lu-PSMA dosimetry
fsysta (%) | NTPb | tSPECTc | OSSd (h) | RMSEKe (%) | μK ± σKf (%) | RMSETe (%) | μT ± σTf (%) |
|---|---|---|---|---|---|---|---|
―g | 1 | t1 | 52 | 7.0 | − 2.8 ± 6.4 | 16 | − 14 ± 7.6 |
25 | 2 | t1 + 0.5 h | 20, 192 | 8.0 | 0.6 ± 8.0 | 13 | − 0.2 ± 13 |
50 | 2 | t1 + 0.5 h | 20, 192 | 7.4 | 0.5 ± 7.4 | 11 | − 0.6 ± 11 |
75 | 2 | t1 + 0.5 h | 20, 192 | 6.6 | 0.2 ± 6.5 | 9.0 | − 1.0 ± 8.9 |
25 | 3 | t2 + 0.5 h | 3, 96, 192 | 7.7 | − 1.0 ± 7.7 | 7.8 | − 1.9 ± 7.5 |
50 | 3 | t2 + 0.5 h | 3, 96, 192 | 7.1 | − 1.0 ± 7.0 | 7.1 | − 2.2 ± 6.8 |
75 | 3 | t2 + 0.5 h | 4, 100, 192 | 6.4 | − 0.7 ± 6.3 | 6.3 | − 1.8 ± 6.0 |
25 | 4 | t3 + 0.5 h | 3, 4, 92, 192 | 7.2 | − 1.1 ± 7.1 | 7.6 | − 1.4 ± 7.5 |
50 | 4 | t3 + 0.5 h | 3, 4, 92, 192 | 6.6 | − 1.3 ± 6.5 | 6.9 | − 1.7 ± 6.7 |
75 | 4 | t3 + 0.5 h | 3, 4, 92, 192 | 5.9 | − 1.3 ± 5.8 | 6.3 | − 2.0 ± 6.0 |