Radiation precautions for inpatient and outpatient 177Lu-DOTATATE peptide receptor radionuclide therapy of neuroendocrine tumours

EJNMMI Physics

Table 3 Mean (SD) [range] measured and estimated dose rates and dose rate per MBq administered activity at 0.1 and 1 m from the mid-abdomen

	Time (hours)	Dose rate (μSv/h)		Dose rate per MBq (nSv/h/MBq)
	Time (hours)	0.1 m	1 m	0.1 m	1 m
¹⁷⁷Lu-DOTATATE Mallinckrodt Inpatient measured	0	407 (83) [250–750]	20 (2) [15–25]	58 (12) [35–99]	3 (0.3) [2.1–3.6]
¹⁷⁷Lu-DOTATATE Mallinckrodt Inpatient estimated	18.1	148 (77) [49–334]	7 (3) [4–15]	21 (11) [5–46]	1 (0.5) [0.4–2]
¹⁷⁷Lu-DOTATATE Mallinckrodt Outpatient estimated	5.2	258 (75) [100–435]	13 (3) [6–20]	37 (10) [14–60]	2 (0.4) [0.8–3]
Lutathera® AAA Outpatient measured	5.7	–	15 (5) [5–25]	–	2 (0.6) [0.6–3]