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Fig. 5 | EJNMMI Physics

Fig. 5

From: EORTC PET response criteria are more influenced by reconstruction inconsistencies than PERCIST but both benefit from the EARL harmonization program

Fig. 5

Representative images of a 66-year-old female with a NSCLC staged T1N2M0 or stage III according to AJCC stadification treated by chemotherapy. This patient was classified as SMD with EORTC classification and PERCIST according to the OSEMPET1/OSEMPET2 standard of reference, while OSEMPET1/PSF ± TOFPET2, a scenario mimicking a system upgrade during a trial led to a PMD with EORTC classification. The use of the EQ.PET methodology correctly classified the patient as SMD. a MIP images and transverse slices at the level of a mediastinal nodal involvement on OSEM and PSF ± TOF reconstructions for baseline scan. b MIP images and transverse slices at the level of a mediastinal nodal involvement on OSEM and PSF ± TOF reconstructions for post-treatment scans. c % change in SULmax and SULpeak for EORTC classification and PERCIST according to the different scenarios

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