Minimum lesion detectability as a measure of PET system performance

EJNMMI Physics

Table 5 Results of the human observer study

Sig to noise	Scanner	1 × 1 × 1 mm voxel					2 × 2 × 2 mm voxel					4 × 4 × 4 mm voxel
Sig to noise	Scanner	16 min	8	4	2	1	16	8	4	2	1	16	8	4	2	1
15:1	Gemini-TF	NA	NA	NA	NA	NA	31	31	63	63	63	63	125	250	125	250
	Vereos	31	31	31	63	125	31	31	63	63	125	31	63	63	63	125
	710	31	63	63	63	125	31	63	63	63	125	31	63	63	63	125
	mCT	31	63	63	63	63	31	31	63	63	125	31	63	63	63	125
	HRRT	63	63	125	250	500	63	63	125	250	500	63	125	125	500	500
7.5:1	Gemini-TF	NA	NA	NA	NA	NA	125	125	125	125	250	125	125	250	250	500
	Vereos	31	63	125	125	250	31	63	125	125	250	63	63	125	125	250
	710	63	63	63	250	250	63	63	125	250	250	63	63	125	250	250
	mCT	63	63	125	125	250	63	63	125	125	250	63	63	125	125	125
	HRRT	125	125	500	500	500	125	125	250	500	500	125	125	250	500	500
3.75:1	Gemini-TF	NA	NA	NA	NA	NA	250	250	250	500	500	250	500	500	500	500
	Vereos	125	125	250	250	500	125	125	250	250	250	125	250	250	250	250
	710	125	125	250	500	1000	125	125	250	500	500	125	125	250	250	500
	mCT	125	250	250	500	500	125	250	250	500	500	125	250	250	250	500
	HRRT	250	500	1000	1000	NSV	250	500	1000	1000	NSV	500	500	1000	1000	NSV
1.85:1	Gemini-TF	NA	NA	NA	NA	NA	500	1000	2000	2000	NSV	1000	2000	2000	2000	2000
	Vereos	500	500	500	1000	2000	500	1000	1000	1000	2000	500	1000	1000	1000	2000
	710	500	1000	2000	1000	NSV	500	500	2000	NSV	NSV	500	500	1000	1000	NSV
	mCT	500	1000	1000	1000	2000	500	1000	1000	1000	2000	500	1000	1000	1000	2000
	HRRT	1000	NSV	NSV	NSV	NSV	2000	2000	NSV	NSV	NSV	2000	NSV	NSV	NSV	NSV

Tabulated are the volumes in units of microliters of the smallest observed sphere for each imaging condition of signal to noise, scan time, and image voxel size for each of the file PET systems. NA or not applicable is used when no data for that setting was recorded and NSV or no sphere visible is used when none of the spheres were visible.