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EJNMMI Physics

Table 3 Impact of quantification method

From: [123I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods

SBR % difference

quantification method

Southampton—BRASS

IRNC

ACSC

Pre calibration

(impact of PVE)

96.0

95.9

Post calibration

(expected = 0)

25.7

33.9

  1. The difference of the un-calibrated Southampton and BRASS databases (first row) represents the magnitude of partial volume losses in human studies. The limitation of phantom calibration in compensating for this effect is reflected in the residual differences of the post-calibration databases
  2. SBR striatal specific binding ratio
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