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Table 2 Toxicity

From: 3D absorbed dose distribution estimated by Monte Carlo simulation in radionuclide therapy with a monoclonal antibody targeting synovial sarcoma

Patient Injected activity (MBq) Liver AD (Gy) Liver toxicity grade Bone marrow AD (Gy) Toxicity grade L Toxicity grade T Toxicity grade A Kidney AD (Gy) Kidney toxicity grade
2 370 1.49 0 0.17 2 0 1 0.25 0
3 1110 3.39 0 0.27 3 1 1 0.76 1
3 bis 1110 3.39 0 0.27 3 1 1 0.76 0
8 1110 8.78 0 1.47 3 1 3 2.27 1
10 370 2.51 0 0.33 1 0 1 0.76 0
11 1110 4.79 0 1.38 3 0 0 2.12 0
14 370 2.97 3 0.54 2 3 3 0.98 0
15 1110 11.22 0 1.33 4 3 2 2.48 0
20 1110 8.52 0 1.81 2 3 1 2.62 0
  1. Absorbed dose (AD) are indicated in Gy for the liver, bone marrow, and kidneys. Toxicity grades are indicated for the liver, leucopenia/lymphopenia (L), thrombocytopenia (T), anemia (A), and kidneys. Patient 3 has been treated with two injections