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Table 2 Toxicity

From: 3D absorbed dose distribution estimated by Monte Carlo simulation in radionuclide therapy with a monoclonal antibody targeting synovial sarcoma

Patient

Injected activity (MBq)

Liver AD (Gy)

Liver toxicity grade

Bone marrow AD (Gy)

Toxicity grade L

Toxicity grade T

Toxicity grade A

Kidney AD (Gy)

Kidney toxicity grade

2

370

1.49

0

0.17

2

0

1

0.25

0

3

1110

3.39

0

0.27

3

1

1

0.76

1

3 bis

1110

3.39

0

0.27

3

1

1

0.76

0

8

1110

8.78

0

1.47

3

1

3

2.27

1

10

370

2.51

0

0.33

1

0

1

0.76

0

11

1110

4.79

0

1.38

3

0

0

2.12

0

14

370

2.97

3

0.54

2

3

3

0.98

0

15

1110

11.22

0

1.33

4

3

2

2.48

0

20

1110

8.52

0

1.81

2

3

1

2.62

0

  1. Absorbed dose (AD) are indicated in Gy for the liver, bone marrow, and kidneys. Toxicity grades are indicated for the liver, leucopenia/lymphopenia (L), thrombocytopenia (T), anemia (A), and kidneys. Patient 3 has been treated with two injections