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Fig. 8 | EJNMMI Physics

Fig. 8

From: Lesion quantification and detection in myocardial 18F-FDG PET using edge-preserving priors and anatomical information from CT and MRI: a simulation study

Fig. 8

Zoomed in images of the lesions reconstructed using the different reconstruction algorithms (example of 1 noise realization). 3i42s + 2i24s + 2i1s iteration scheme. The RD and the TV priors represent a good choice in case no anatomical information is available, if the anatomical information does not highlight the lesions or if the anatomical information is mismatched (see Bowsher (HRCT) or Bowsher (MR)-shift). When the anatomical image is matching the PET dataset and it clearly differentiates between healthy and scarred tissue, then it is definitely the preferred choice (Bowsher(MR)-perf). Please note that the OSEM3D reconstructions suffer more than others from severe noise; this is due to the long iteration scheme, applied to ensure convergence and consistency with the other reconstructions. The suffix -shift indicates the case where the anatomy is displaced by 2 mm in the x and z direction, while -mism represents the case where the heart in the anatomical information has the same morphology but it is in a slightly different cardiac phase relative to the PET dataset

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