Figure 8

Histogram of 16 separate simulations, weighted to macroscopic distribution. The histogram reflects the microscopic absorbed dose distributions (per voxel) in 16 biopsies weighted according to macroscopic mean activity concentration measurements in 41 biopsies, shown in Figure 1. The mean absorbed dose was 43 ± 38 Gy; CV 0.89, the median absorbed dose 36 Gy, and the 10^th, 25^th, 75^th, and 90^th percentiles at 15, 20, 58, and 79 Gy. A tail of high absorbed doses are found between 145 and 1200 Gy; this will only affect 1% of the total parenchyma volume, whereas 45% of the parenchyma volume will achieve absorbed doses <30 Gy. 90% of the voxels were found from 10 to 97 Gy. A gathering of voxels was observed in the interval of 600 to 800 Gy, but these voxels formed only 0.17% of the total volume. As the few voxels found above 800 Gy are not visually discernible, the histogram is truncated, accordingly.