Fig. 5

Coronal views of [¹⁸F]FDG K_i parametric images from Patlak linearization (A) and [¹⁸F]DPA-714 V_T parametric images from Logan linearization (B) using different calibrated input functions and the same whole body reconstruction (EARL 2). All IDIFs were extracted using AA location except for EARL2_DA and EARL2_LV. For [¹⁸F]FDG, no significant visual differences are seen between K_i parametric images using the different IDIFs. For [¹⁸F]DPA-714, compared to the V_T parametric images obtained with input function using continuous arterial sampler (reference), visual differences are seen using EARL2_DA and EARL2_LV IDIFs, significantly in lungs (orange arrows) and liver (blue arrows) (AA: Ascending Aorta, DA: Descending Aorta, LV: Left Ventricular Cavity, it: iterations, mat440: matrix 440 × 440, MRD: maximum ring differences, abs: absolute scatter correction methods)