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  1. 18F-FDG PET is often utilized to determine BNCT selection due to the limited availability of 18F-BPA PET, which is performed by synthesizing 18F into the boron drug used for BNCT, although the uptake mechanisms b...

    Authors: Tetsu Nakaichi, Satoshi Nakamura, Kimiteru Ito, Kana Takahashi, Mihiro Takemori, Tairo Kashihara, Kouji Kunito, Naoya Murakami, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Shohei Mikasa, Teiji Nishio, Hiroyuki Okamoto, Jun Itami, Hiroaki Kurihara…
    Citation: EJNMMI Physics 2022 9:89
  2. This study evaluated the physical performance of a positron emission tomography (PET) system dedicated to the head and breast according to the National Electrical Manufacturers Association (NEMA) NU2-2012 stan...

    Authors: Daisuke Morimoto-Ishikawa, Kohei Hanaoka, Shota Watanabe, Takahiro Yamada, Yoshiyuki Yamakawa, Suzuka Minagawa, Shiho Takenouchi, Atsushi Ohtani, Tetsuro Mizuta, Hayato Kaida and Kazunari Ishii
    Citation: EJNMMI Physics 2022 9:88
  3. Recently, total-body PET/CT systems with an extended axial field-of-view (aFOV) became commercially available which allow acquiring physiologic information of multiple organs simultaneously. However, the nomin...

    Authors: Ivo Rausch, Julia G. Mannheim, Jürgen Kupferschläger, Christian la Fougère and Fabian P. Schmidt
    Citation: EJNMMI Physics 2022 9:87
  4. Accurate quantification of radioactivity in a source of interest relies on accurate registration between SPECT and anatomical images, and appropriate correction of partial volume effects (PVEs). For small volu...

    Authors: Lily Carnegie-Peake, Jan Taprogge, Iain Murray, Glenn D. Flux and Jonathan Gear
    Citation: EJNMMI Physics 2022 9:86
  5. We evaluated the effects of acquisition time, energy window width, and matrix size on the image quality, quantitation, and diagnostic performance of whole-body 99mTc-HMDP SPECT/CT in the primary metastasis stagin...

    Authors: Samuli Arvola, Marko Seppänen, Kirsi L. Timonen, Pentti Rautio, Otto Ettala, Mikael Anttinen, Peter J. Boström and Tommi Noponen
    Citation: EJNMMI Physics 2022 9:85
  6. COVID-19 infection, especially in cases with pneumonia, is associated with a high rate of pulmonary embolism (PE). In patients with contraindications for CT pulmonary angiography (CTPA) or non-diagnostic CTPA,...

    Authors: Sonia Baeza, Debora Gil, Ignasi Garcia-Olivé, Maite Salcedo-Pujantell, Jordi Deportós, Carles Sanchez, Guillermo Torres, Gloria Moragas and Antoni Rosell
    Citation: EJNMMI Physics 2022 9:84

    The Correction to this article has been published in EJNMMI Physics 2023 10:13

  7. The purpose of the present study was to elucidate the correlation between standardized uptake value (SUV) and volume-based parameters measured by quantitative [99mTc]Tc-methylene diphosphonate (MDP) single photon...

    Authors: Kenichi Tanaka, Takashi Norikane, Katsuya Mitamura, Yuka Yamamoto, Yukito Maeda, Kengo Fujimoto, Yasukage Takami, Mariko Ishimura, Hanae Arai-Okuda, Yoichiro Tohi, Nobuyuki Kudomi, Mikio Sugimoto and Yoshihiro Nishiyama
    Citation: EJNMMI Physics 2022 9:83
  8. To establish a proof-of-concept study using a phantom model to allow the fusion of preoperative single-photon emission computed tomography (SPECT) combined with computed tomography (CT), also known as SPECT/CT...

    Authors: Lise Lecointre, Juan Verde, Fabrice Hubele, Julien Salvadori, Laurent Goffin, Chérif Akladios and Benoît Gallix
    Citation: EJNMMI Physics 2022 9:81
  9. Patient’s breathing affects the quality of chest images acquired with positron emission tomography/computed tomography (PET/CT) studies. Movement correction is required to optimize PET quantification in clinic...

    Authors: Andrea Martinez-Movilla, Michael Mix, Irene Torres-Espallardo, Elena Teijeiro, Pilar Bello, Dimos Baltas, Luis Martí-Bonmatí and Montserrat Carles
    Citation: EJNMMI Physics 2022 9:80
  10. We aimed to investigate the effect and significance of the rotation method with variable-angle anterior probe corrected for the depth of two kidneys on the determination of glomerular filtration rate (GFR) in ...

    Authors: Hua Wei, Ke Han, Jiaojiao Wu, Guang Hu, Zhifang Wu, Hongliang Wang, Xiaoshan Guo, Yansong Hou, Rui Wang and Sijin Li
    Citation: EJNMMI Physics 2022 9:79
  11. Since it was first approved in Europe in 2016, the gallium-68 (68Ga) radiopharmaceutical [68Ga]Ga-DOTA-TOC has been widely used for imaging of somatostatin receptor (SSTR) positive tumours using positron emission...

    Authors: Mercedes Riveira-Martin, Lara Struelens, Werner Schoonjans, Isaac Sánchez-Díaz, Jose Muñoz Iglesias, Óscar Ferreira Dávila, Francisco Javier Salvador Gómez, Manuel Salgado Fernández and Antonio López Medina
    Citation: EJNMMI Physics 2022 9:75
  12. Excellent performance characteristics of the Vision Quadra PET/CT, e.g. a substantial increase in sensitivity, allow for precise measurements of image-derived input functions (IDIF) and tissue time activity cu...

    Authors: Joyce van Sluis, Johannes H. van Snick, Adrienne H. Brouwers, Walter Noordzij, Rudi A. J. O. Dierckx, Ronald J. H. Borra, Adriaan A. Lammertsma, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart, Maqsood Yaqub, Charalampos Tsoumpas and Ronald Boellaard
    Citation: EJNMMI Physics 2022 9:74
  13. The 2018 BNMS Glomerular Filtration Rate (GFR) guidelines recommend a single-sample technique with the sampling time dictated by the expected renal function, but this is not known with any accuracy before the ...

    Authors: Helena McMeekin, Sam Townrow, Mark Barnfield, Andy Bradley, Ben Fongenie, Daniel R. McGowan, Matthew Memmott, Charlotte A. Porter, Fred Wickham, Nick Vennart and Maria Burniston
    Citation: EJNMMI Physics 2022 9:73
  14. An open-source, extensible medical viewing platform is described, called the TriDFusion image viewer (3DF). The 3DF addresses many broad unmet needs in nuclear medicine research; it provides a viewer with seve...

    Authors: Daniel Lafontaine, C. Ross Schmidtlein, Assen Kirov, Ryan P. Reddy, Simone Krebs, Heiko Schöder and John L. Humm
    Citation: EJNMMI Physics 2022 9:72
  15. PET/MRI is an attractive imaging modality due to the complementary nature of MRI and PET. Obtaining high quality small animal PET/MRI results is key for the translation of novel PET/MRI agents and techniques t...

    Authors: Alyssa C. Pollard, Jorge de la Cerda, F. William Schuler, Charles V. Kingsley, Seth T. Gammon and Mark D. Pagel
    Citation: EJNMMI Physics 2022 9:70
  16. To confirm the performance of the first hemispherical positron emission tomography (PET) for the brain (Vrain) that we developed to visualise the small nuclei in the deep brain area, we compared 18F-fluorodeoxygl...

    Authors: Miwako Takahashi, Go Akamatsu, Yuma Iwao, Hideaki Tashima, Eiji Yoshida and Taiga Yamaya
    Citation: EJNMMI Physics 2022 9:69
  17. Performance assessment of positron emission tomography (PET) scanners is crucial to guide clinical practice with efficiency. Even though clinical data are the final target, their use to characterize systems re...

    Authors: Quentin Maronnier, Frédéric Courbon and Olivier Caselles
    Citation: EJNMMI Physics 2022 9:68
  18. The aim of this study is to elucidate the difference in absorbed dose (Dabs) patterns in radiopharmaceutical therapies between alpha emitters (225Ac) and beta emitters (177Lu) when targeting cancer-associated fib...

    Authors: Jonathan Tranel, Stig Palm, Stephen A. Graves, Felix Y. Feng and Thomas A. Hope
    Citation: EJNMMI Physics 2022 9:67
  19. [18F] FDG PET-CT has an important role in the initial staging of lung cancer; however, accurate differentiation between activity in malignant and benign intrathoracic lymph nodes on PET-CT scans can be challengin...

    Authors: Sara S. A. Laros, Dennis Dieckens, Stephan P. Blazis and Johannes A. van der Heide
    Citation: EJNMMI Physics 2022 9:66
  20. Based on theoretical and preclinical results, terbium-161 may be a valid alternative to lutetium-177 and yttrium-90 in radionuclide therapies. The large low-energy electron emission from terbium-161 is a favor...

    Authors: Jens Hemmingsson, Johanna Svensson, Nicholas P. van der Meulen, Cristina Müller and Peter Bernhardt
    Citation: EJNMMI Physics 2022 9:65
  21. The clinical utility of radiomics is hampered by a high correlation between the large number of features analysed which may result in the “bouncing beta” phenomenon which could in part explain why in a similar...

    Authors: DeLeu Anne-Leen, Sathekge Machaba, Maes Alex, De Spiegeleer Bart, Beels Laurence, Sathekge Mike, Pottel Hans and Christophe Van de Wiele
    Citation: EJNMMI Physics 2022 9:64
  22. Efforts have been made both to avoid invasive blood sampling and to shorten the scan duration for dynamic positron emission tomography (PET) imaging. A total-body scanner, such as the uEXPLORER PET/CT, can rel...

    Authors: Zhenguo Wang, Yaping Wu, Xiaochen Li, Yan Bai, Hongzhao Chen, Jie Ding, Chushu Shen, Zhanli Hu, Dong Liang, Xin Liu, Hairong Zheng, Yongfeng Yang, Yun Zhou, Meiyun Wang and Tao Sun
    Citation: EJNMMI Physics 2022 9:63
  23. The total-body positron emission tomography (PET) scanner provides an unprecedented opportunity to scan the whole body simultaneously, thanks to its long axial field of view and ultrahigh temporal resolution. ...

    Authors: Tao Sun, Yaping Wu, Wei Wei, Fangfang Fu, Nan Meng, Hongzhao Chen, Xiaochen Li, Yan Bai, Zhenguo Wang, Jie Ding, Debin Hu, Chaojie Chen, Zhanli Hu, Dong Liang, Xin Liu, Hairong Zheng…
    Citation: EJNMMI Physics 2022 9:62
  24. Radiotracer extravasations, caused largely by faulty tracer injections, can occur in up to 23% of 18F-fluorodeoxyglucose (FDG) PET/CT scans and negatively impact radiological review and tracer quantification. Con...

    Authors: Steve Perrin, Jackson W. Kiser, Josh Knowland and Spencer L. Bowen
    Citation: EJNMMI Physics 2022 9:61
  25. Contemporary PET/CT scanners can use 70-min dynamic whole-body (D-WB) PET to generate more quantitative information about FDG uptake than just the SUV by generating parametric images of FDG metabolic rate (MRFDG)...

    Authors: André H. Dias, Anne M. Smith, Vijay Shah, David Pigg, Lars C. Gormsen and Ole L. Munk
    Citation: EJNMMI Physics 2022 9:60
  26. Currently, there is no consensus on the optimal partial volume correction (PVC) algorithm for oncology imaging. Several existing PVC methods require knowledge of the reconstructed resolution, usually as the po...

    Authors: Rebecca Gillen, Kjell Erlandsson, Ana M. Denis-Bacelar, Kris Thielemans, Brian F. Hutton and Sarah J. McQuaid
    Citation: EJNMMI Physics 2022 9:59
  27. PET nuclides can have a considerable influence on the spatial resolution and image quality of PET/CT scans, which can influence diagnostics in oncology, for example. The individual impact of the positron energ...

    Authors: Anja Braune, Liane Oehme, Robert Freudenberg, Frank Hofheinz, Jörg van den Hoff, Jörg Kotzerke and Sebastian Hoberück
    Citation: EJNMMI Physics 2022 9:58
  28. In 2016, the International Commission on Radiological Protection (ICRP) published the results of Monte Carlo simulations performed using updated and anatomically realistic voxelized phantoms. The resulting spe...

    Authors: Shalini Subramanian, Bin He, Eric Frey, Derek W. Jokisch, Wesley Bolch and George Sgouros
    Citation: EJNMMI Physics 2022 9:57
  29. To evaluate the effect of combining positron range correction (PRC) with point-spread-function (PSF) correction and to compare different methods of implementation into iterative image reconstruction for 124I-PET ...

    Authors: Hunor Kertész, Maurizio Conti, Vladimir Panin, Jorge Cabello, Deepak Bharkhada, Thomas Beyer, Laszlo Papp, Walter Jentzen, Jacobo Cal-Gonzalez, Joaquín L. Herraiz, Alejandro López-Montes and Ivo Rausch
    Citation: EJNMMI Physics 2022 9:56
  30. Deep convolutional neural networks have demonstrated robust and reliable PET attenuation correction (AC) as an alternative to conventional AC methods in integrated PET/MRI systems. However, its whole-body impl...

    Authors: Sahar Ahangari, Anders Beck Olin, Marianne Kinggård Federspiel, Bjoern Jakoby, Thomas Lund Andersen, Adam Espe Hansen, Barbara Malene Fischer and Flemming Littrup Andersen
    Citation: EJNMMI Physics 2022 9:55
  31. Dead-time correction is required for accurate quantitative SPECT-based dosimetry in the context of personalised 177Lu radiopharmaceutical therapy. We aimed to evaluate the impact of applying dead-time correction ...

    Authors: Alessandro Desy, Guillaume F. Bouvet, Nancy Lafrenière, Atefeh Zamanian, Philippe Després and Jean-Mathieu Beauregard
    Citation: EJNMMI Physics 2022 9:54
  32. Machine learning studies require a large number of images often obtained on different PET scanners. When merging these images, the use of harmonized images following EARL-standards is essential. However, when ...

    Authors: Elisabeth Pfaehler, Daniela Euba, Andreas Rinscheid, Otto S. Hoekstra, Josee Zijlstra, Joyce van Sluis, Adrienne H. Brouwers, Constantin Lapa and Ronald Boellaard
    Citation: EJNMMI Physics 2022 9:53
  33. Lead-212 (212Pb) is a promising radionuclide for targeted therapy, as it decays to α-particle emitter bismuth-212 (212Bi) via β-particle emission. This extends the problematic short half-life of 212Bi. In prepara...

    Authors: Monika Kvassheim, Mona-Elisabeth R. Revheim and Caroline Stokke
    Citation: EJNMMI Physics 2022 9:52

    The Correction to this article has been published in EJNMMI Physics 2022 9:71

  34. Myocardial perfusion imaging (MPI) using positron emission tomography (PET) tracers is an essential tool in investigating diseases and treatment responses in cardiology. 82Rubidium (82Rb)-PET imaging is advantage...

    Authors: Malte Jensen, Simon Bentsen, Andreas Clemmensen, Jacob Kildevang Jensen, Johanne Madsen, Jonas Rossing, Anna Laier, Philip Hasbak, Andreas Kjaer and Rasmus Sejersten Ripa
    Citation: EJNMMI Physics 2022 9:51
  35. Partial volume correction with anatomical magnetic resonance (MR) images (MR-PVC) is useful for accurately quantifying tracer uptake on brain positron emission tomography (PET) images. However, MR segmentation...

    Authors: Keisuke Matsubara, Masanobu Ibaraki and Toshibumi Kinoshita
    Citation: EJNMMI Physics 2022 9:50
  36. The prediction of response is one of the major challenges in radiation-based therapies. Although the selection of accurate linear–quadratic model parameters is essential for the estimation of radiation respons...

    Authors: Yaser H. Gholami, Kathy P. Willowson and Dale L. Bailey
    Citation: EJNMMI Physics 2022 9:49
  37. SwiftScan single-photon emission computed tomography (SPECT) is a recently released scanning technique with data acquired when the detector is stationary and when it moves from one view to the next. The influe...

    Authors: Takuro Shiiba, Yuya Sekikawa, Shinji Tateoka, Nobutaka Shinohara, Yuuki Inoue, Yasuyoshi Kuroiwa, Takashi Tanaka, Yasushi Kihara and Takuroh Imamura
    Citation: EJNMMI Physics 2022 9:48
  38. In recent years, a lot of effort has been put in the enhancement of medical imaging using artificial intelligence. However, limited patient data in combination with the unavailability of a ground truth often p...

    Authors: Julian Leube, Johan Gustafsson, Michael Lassmann, Maikol Salas-Ramirez and Johannes Tran-Gia
    Citation: EJNMMI Physics 2022 9:47
  39. The development of new targeted alpha therapies motivates improving alpha particle dosimetry. For alpha particles, microscopic targets must be considered to estimate dosimetric quantities that can predict the ...

    Authors: Emma Mellhammar, Magnus Dahlbom, Oskar Vilhelmsson-Timmermand and Sven-Erik Strand
    Citation: EJNMMI Physics 2022 9:46
  40. The present study aimed to explore the boundary of acquisition time and propose an optimized acquisition time range for total-body positron emission tomography (PET)/computed tomography (CT) oncological imagin...

    Authors: Yibo He, Yushen Gu, Haojun Yu, Bing Wu, Siyang Wang, Hui Tan, Yanyan Cao, Shuguang Chen, Xiuli Sui, Yiqiu Zhang and Hongcheng Shi
    Citation: EJNMMI Physics 2022 9:45
  41. To evaluate if satisfactory post-therapeutic image-based dosimetry can be achieved for Lu-177-DOTATATE treatments using a reduced number of image acquisitions to improve patient comfort and reduce economical c...

    Authors: Oscar Ardenfors, Joachim N. Nilsson, Daniel Thor and Cecilia Hindorf
    Citation: EJNMMI Physics 2022 9:44
  42. The SAFIR prototype insert is a preclinical Positron Emission Tomography (PET) scanner built to acquire dynamic images simultaneously with a 7 T Bruker Magnetic Resonance Imaging (MRI) scanner. The insert is d...

    Authors: Parisa Khateri, Werner Lustermann, Christian Ritzer, Charalampos Tsoumpas and Günther Dissertori
    Citation: EJNMMI Physics 2022 9:42
  43. 211At, a promising alpha-particle-emitting radionuclide, can easily volatilize and contaminate the environment. To safely manage this unique alpha-particle-emitting radionuclide, we investigated the permeability ...

    Authors: Kazunobu Ohnuki, Mitsuyoshi Yoshimoto, Hiromitsu Haba, Shino Manabe, Hiroki Takashima, Masahiro Yasunaga, Yasumasa Takenaka and Hirofumi Fujii
    Citation: EJNMMI Physics 2022 9:39

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