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EJNMMI Physics
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  1. Quantitative single photon emission computed tomography (SPECT) is challenging, especially for pancreatic beta cell imaging with 111In-exendin due to high uptake in the kidneys versus much lower uptake in the nea...

    Authors: Wietske Woliner-van der Weg, Laura N. Deden, Antoi P. W. Meeuwis, Maaike Koenrades, Laura H. C. Peeters, Henny Kuipers, Geert Jan Laanstra, Martin Gotthardt, Cornelis H. Slump and Eric P. Visser
    Citation: EJNMMI Physics 2016 3:29
    Content type: Original Research Published on:

  2. Positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) is now a routine procedure for the management of cancer patients. Intravenous administration of FDG is sometimes halted due to troubles. In suc...

    Authors: Kenta Sakaguchi, Makoto Hosono, Tomomi Imamura, Naomi Takahara, Misa Hayashi, Yuko Yakushiji, Kazunari Ishii, Tatsuro Uto and Takamichi Murakami
    Citation: EJNMMI Physics 2016 3:28
    Content type: Original research Published on:

  3. The impact of increased energy resolution of cadmium–zinc–telluride (CZT) cameras on the assessment of left ventricular function under dual-isotope conditions (99mTc and 123I) remains unknown.

    Authors: Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini and Alain Manrique
    Citation: EJNMMI Physics 2016 3:27
    Content type: Original research Published on:

  4. The point spread function (PSF) of positron emission tomography (PET) depends on the position across the field of view (FOV). Reconstruction based on PSF improves spatial resolution and quantitative accuracy. ...

    Authors: Taisuke Murata, Kenta Miwa, Noriaki Miyaji, Kei Wagatsuma, Tomoyuki Hasegawa, Keiichi Oda, Takuro Umeda, Takashi Iimori, Yoshitada Masuda, Takashi Terauchi and Mitsuru Koizumi
    Citation: EJNMMI Physics 2016 3:26
    Content type: Original article Published on:

  5. Both enantiomers of [18F]flubatine are new radioligands for neuroimaging of α4β2 nicotinic acetylcholine receptors with positron emission tomography (PET) exhibiting promising pharmacokinetics which makes them at...

    Authors: Mathias Kranz, Bernhard Sattler, Solveig Tiepolt, Stephan Wilke, Winnie Deuther-Conrad, Cornelius K. Donat, Steffen Fischer, Marianne Patt, Andreas Schildan, Jörg Patt, René Smits, Alexander Hoepping, Jörg Steinbach, Osama Sabri and Peter Brust
    Citation: EJNMMI Physics 2016 3:25
    Content type: Original research Published on:

  6. Recent advancements in PET instrumentation have made the non-invasive assessment of cardiovascular function in small animals a reality. The majority of small animal PET systems use stationary detector gantries...

    Authors: Paul R. Territo, Amanda A. Riley, Brian P. McCarthy and Gary D. Hutchins
    Citation: EJNMMI Physics 2016 3:24
    Content type: Short communication Published on:

  7. While fluorodeoxyglucose (FDG) and amyloid PET is valuable for patient management, research, and clinical trial of therapeutics on Alzheimer’s disease, the specific details of the PET scanning method including...

    Authors: Yasuhiko Ikari, Go Akamatsu, Tomoyuki Nishio, Kenji Ishii, Kengo Ito, Takeshi Iwatsubo and Michio Senda
    Citation: EJNMMI Physics 2016 3:23
    Content type: Original research Published on:

  8. For tumour imaging with PET, the literature proposes to administer a patient-specific FDG activity that depends quadratically on a patient’s body weight. However, a practical approach on how to implement such ...

    Authors: Daniëlle Koopman, Jochen A. C. van Osch, Pieter L. Jager, Carlijn J. A. Tenbergen, Siert Knollema, Cornelis H. Slump and Jorn A. van Dalen
    Citation: EJNMMI Physics 2016 3:22
    Content type: Original research Published on:

  9. 177Lu-DOTATATE is a valuable treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. Though well tolerated in general, bone marrow to...

    Authors: Johanna Svensson, Tobias Rydén, Linn Hagmarker, Jens Hemmingsson, Bo Wängberg and Peter Bernhardt
    Citation: EJNMMI Physics 2016 3:21
    Content type: Original research Published on:

  11. The search for novel image contrasts has been a major driving force in the magnetic resonance (MR) research community, in order to gain further information on the body’s physiological and pathological conditions.

    Authors: B. Wu, G. Warnock, M. Zaiss, C. Lin, M. Chen, Z. Zhou, L. Mu, D. Nanz, R. Tuura and G. Delso
    Citation: EJNMMI Physics 2016 3:19
    Content type: Review Published on:

  12. The purpose of this study is to specify a simple procedure for a robust data conversion of radioactivity value between plastic scintillator (PL) and NaI scintillator (NaI) devices.

    Authors: Takeshi Hara, Tadahiko Ishihara, Takahiko Asano, Masayuki Matsuo, Tetsuro Katafuchi and Hiroshi Fujita
    Citation: EJNMMI Physics 2016 3:18
    Content type: Short communication Published on:

  13. The use of selective internal radiation therapy (SIRT) is rapidly increasing, and the need for quantification and dosimetry is becoming more widespread to facilitate treatment planning and verification. The ai...

    Authors: Jonathan I. Gear, Craig Cummings, Allison J. Craig, Antigoni Divoli, Clive D. C. Long, Michael Tapner and Glenn D. Flux
    Citation: EJNMMI Physics 2016 3:17
    Content type: Original research Published on:

  14. The recent spread of positron emission tomography-computed tomography (PET/CT) poses extremity dosimetry challenges. The question arose whether the radiation dose measured by the ring thermoluminescent dosimet...

    Authors: Fabien Salesses, Paul Perez, Aline E. Maillard, Julie Blanchard, Sabine Mallard and Laurence Bordenave
    Citation: EJNMMI Physics 2016 3:16
    Content type: Original research Published on:

  15. Somatostatin analogue-based radionuclide therapy with 177Lu-DOTATATE is an important treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. In addition to the ki...

    Authors: Johanna Svensson, Linn Hagmarker, Tobias Magnander, Bo Wängberg and Peter Bernhardt
    Citation: EJNMMI Physics 2016 3:15
    Content type: Original research Published on:

  16. The purpose of this study was twofold: to evaluate the quantitative stability of a SPECT/CT gamma camera over time and to determine if daily flood acquisitions can reliably serve as calibration factors for qua...

    Authors: Wendy A. McDougald, Robert S. Miyaoka, Adam M. Alessio, Robert L. Harrison and Thomas K. Lewellen
    Citation: EJNMMI Physics 2016 3:14
    Content type: Original research Published on:

  17. The study aims to develop and validate an automatic delineation method for estimating red bone marrow (RM) activity concentration and absorbed dose in 89Zr positron emission tomography/computed tomography (PET/CT...

    Authors: N.E. Makris, R. Boellaard, C.W. Menke, A.A. Lammertsma and M.C. Huisman
    Citation: EJNMMI Physics 2016 3:13
    Content type: Original research Published on:

  18. Patient-specific absorbed dose calculations for molecular radiotherapy require accurate activity quantification. This is commonly derived from Single-Photon Emission Computed Tomography (SPECT) imaging using a...

    Authors: Andrew P. Robinson, Jill Tipping, David M. Cullen, David Hamilton, Richard Brown, Alex Flynn, Christopher Oldfield, Emma Page, Emlyn Price, Andrew Smith and Richard Snee
    Citation: EJNMMI Physics 2016 3:12
    Content type: Original Research Published on:

  19. We present a quick and easy method to perform quantitatively accurate PET scans of typical water-filled PET plastic shell phantoms on the Siemens Biograph mMR PET/MR system.

    Authors: Sune H. Keller, Björn Jakoby, Susanne Svalling, Andreas Kjaer, Liselotte Højgaard and Thomas L. Klausen
    Citation: EJNMMI Physics 2016 3:11
    Content type: Short communication Published on:

  20. A brain single-photon emission computed tomography (SPECT) system using cadmium telluride (CdTe) solid-state detectors was previously developed. This CdTe-SPECT system is suitable for simultaneous dual-radionu...

    Authors: Wataru Takeuchi, Atsuro Suzuki, Tohru Shiga, Naoki Kubo, Yuichi Morimoto, Yuichiro Ueno, Keiji Kobashi, Kikuo Umegaki and Nagara Tamaki
    Citation: EJNMMI Physics 2016 3:10
    Content type: Original research Published on:

  21. The limited spatial resolution of the clinical PET scanners results in image blurring and does not allow for accurate quantification of very thin or small structures (known as partial volume effect). In cardiac i...

    Authors: Anna Turco, Johan Nuyts, Olivier Gheysens, Jürgen Duchenne, Jens-Uwe Voigt, Piet Claus and Kathleen Vunckx
    Citation: EJNMMI Physics 2016 3:9
    Content type: Original Research Published on:

  23. Integrated PET/MRI with hyperpolarized 13C magnetic resonance spectroscopic imaging (13C-MRSI) offers simultaneous, dual-modality metabolic imaging. A prerequisite for the use of simultaneous imaging is the absen...

    Authors: Adam E. Hansen, Flemming L. Andersen, Sarah T. Henriksen, Alexandre Vignaud, Jan H. Ardenkjaer-Larsen, Liselotte Højgaard, Andreas Kjaer and Thomas L. Klausen
    Citation: EJNMMI Physics 2016 3:7
    Content type: Original research Published on:

  24. CATI is a French initiative launched in 2010 to handle the neuroimaging of a large cohort of subjects recruited for an Alzheimer’s research program called MEMENTO. This paper presents our test protocol and res...

    Authors: Marie-Odile Habert, Sullivan Marie, Hugo Bertin, Moana Reynal, Jean-Baptiste Martini, Mamadou Diallo, Aurélie Kas and Régine Trébossen
    Citation: EJNMMI Physics 2016 3:6
    Content type: Original research Published on:

  26. Dopamine transporter (DaT) imaging (DaTSCAN) is useful for the differential diagnosis of parkinsonian syndromes. Visual evaluation of DaTSCAN images represents the generally accepted diagnostic method, but it ...

    Authors: Antonio Augimeri, Andrea Cherubini, Giuseppe Lucio Cascini, Domenico Galea, Maria Eugenia Caligiuri, Gaetano Barbagallo, Gennarina Arabia and Aldo Quattrone
    Citation: EJNMMI Physics 2016 3:4
    Content type: Original research Published on:

  27. While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already built in the early 1980s, limited clinical studies were acquired on these scanners. PET was still a research tool, a...

    Authors: S. Vandenberghe, E. Mikhaylova, E. D’Hoe, P. Mollet and J. S. Karp
    Citation: EJNMMI Physics 2016 3:3
    Content type: Review Published on:

  28. Obtaining the arterial input function (AIF) from image data in dynamic positron emission tomography (PET) examinations is a non-invasive alternative to arterial blood sampling. In simultaneous PET/magnetic res...

    Authors: Thies H. Jochimsen, Vilia Zeisig, Jessica Schulz, Peter Werner, Marianne Patt, Jörg Patt, Antje Y. Dreyer, Johannes Boltze, Henryk Barthel, Osama Sabri and Bernhard Sattler
    Citation: EJNMMI Physics 2016 3:2
    Content type: Original Research Published on:

  29. Low uptake ratios, high noise, poor resolution, and low contrast all combine to make the detection of neuroendocrine liver tumours by 111In-octreotide single photon emission tomography (SPECT) imaging a challenge...

    Authors: Tobias Magnander, E. Wikberg, J. Svensson, P. Gjertsson, B. Wängberg, M. Båth and Peter Bernhardt
    Citation: EJNMMI Physics 2016 3:1
    Content type: Original research Published on:

  30. Recently, significant interest in 44Sc as a tracer for positron emission tomography (PET) imaging has been observed. Unfortunately, the co-emission by 44Sc of high-energy γ rays (E γ = ...

    Authors: Rafał Walczak, Seweryn Krajewski, Katarzyna Szkliniarz, Mateusz Sitarz, Kamel Abbas, Jarosław Choiński, Andrzej Jakubowski, Jerzy Jastrzębski, Agnieszka Majkowska, Federica Simonelli, Anna Stolarz, Agnieszka Trzcińska, Wiktor Zipper and Aleksander Bilewicz
    Citation: EJNMMI Physics 2015 2:33
    Content type: Original research Published on:

  31. A feasibility study was done to assess the capability of digital silicon photomultipliers to measure the Cherenkov luminescence emitted by a β source. Cherenkov luminescence imaging (CLI) is possible with a charg...

    Authors: Esther Ciarrocchi, Nicola Belcari, Alberto Del Guerra, Simon R. Cherry, Adrienne Lehnert, William C. J. Hunter, Wendy McDougald, Robert S. Miyaoka and Paul E. Kinahan
    Citation: EJNMMI Physics 2015 2:32
    Content type: Original Research Published on:

  32. Small-animal imaging has become an important technique for the development of new radiotracers, drugs and therapies. Many laboratories have now a combination of different small-animal imaging systems, which ar...

    Authors: Christian Vanhove, Jens P. Bankstahl, Stefanie D. Krämer, Eric Visser, Nicola Belcari and Stefaan Vandenberghe
    Citation: EJNMMI Physics 2015 2:31
    Content type: Teaching file Published on:

  33. Authors: Ana Mota, Vesna Cuplov, Ivana Drobnjak, John Dickson, Julien Bert, Ninon Burgos, Jorge Cardoso, Marc Modat, Sebastien Ourselin, Jonathan Schott, Kjell Erlandsson, Brian Hutton and Kris Thielemans
    Citation: EJNMMI Physics 2015 2:30
    Content type: Erratum Published on:

    The original article was published in EJNMMI Physics 2015 2:A44

  37. The purpose of the study is to evaluate the physical performance of a Biograph mCT Flow 64-4R PET/CT system (Siemens Healthcare, Germany) and to compare clinical image quality in step-and-shoot (SS) and contin...

    Authors: Ivo Rausch, Jacobo Cal-González, David Dapra, Hans Jürgen Gallowitsch, Peter Lind, Thomas Beyer and Gregory Minear
    Citation: EJNMMI Physics 2015 2:26
    Content type: Original research Published on:

  38. The aim of this study was to develop and validate an automated method for extracting forward stroke volume (FSV) using indicator dilution theory directly from dynamic positron emission tomography (PET) studies...

    Authors: Hendrik Johannes Harms, Lars Poulsen Tolbod, Nils Henrik Stubkjær Hansson, Tanja Kero, Lovisa Holm Orndahl, Won Yong Kim, Tomas Bjerner, Kirsten Bouchelouche, Henrik Wiggers, Jørgen Frøkiær and Jens Sörensen
    Citation: EJNMMI Physics 2015 2:25
    Content type: Original research Published on:

  39. Radionuclide therapy can be individualized by performing dosimetry. To determine absorbed organ doses in 177Lu-DOTATATE therapy, three methods based on activity concentrations are currently in use: the small volu...

    Authors: Mattias Sandström, Ezgi Ilan, Anna Karlberg, Silvia Johansson, Nanette Freedman and Ulrike Garske-Román
    Citation: EJNMMI Physics 2015 2:24
    Content type: Original research Published on:

  42. The purpose of this study was to evaluate the utility of bellows-based respiratory compensation and navigated hepatobiliary phase imaging to correct for respiratory motion in the setting of dedicated liver PET...

    Authors: Thomas A. Hope, Emily F. Verdin, Emily K. Bergsland, Michael A. Ohliger, Carlos U. Corvera and Eric K. Nakakura
    Citation: EJNMMI Physics 2015 2:21
    Content type: Original research Published on:

  43. Advances in gamma camera technology and the emergence of a number of new theranostic radiopharmaceutical pairings have re-awakened interest in in vivo quantification with single-photon-emitting radionuclides. ...

    Authors: Dale L. Bailey, Thomas M. Hennessy, Kathy P. Willowson, E. Courtney Henry, David L.H. Chan, Alireza Aslani and Paul J. Roach
    Citation: EJNMMI Physics 2015 2:20
    Content type: Original research Published on:

  44. Non-uniformity influences the interpretation of nuclear medicine based images and consequently their use in treatment planning and monitoring. However, no standardised method for evaluating and ranking heterog...

    Authors: Jonas Grafström, Hanna-Stina Ahlzén and Sharon Stone-Elander
    Citation: EJNMMI Physics 2015 2:19
    Content type: Original research Published on:

  45. In integrated PET/MR hybrid imaging the evaluation of PET performance characteristics according to the NEMA standard NU 2–2007 is challenging because of incomplete MR-based attenuation correction (AC) for phan...

    Authors: Susanne Ziegler, Bjoern W. Jakoby, Harald Braun, Daniel H. Paulus and Harald H. Quick
    Citation: EJNMMI Physics 2015 2:18
    Content type: Original research Published on:

  46. Generally, attenuation correction is made by incorporating a linear attenuation coefficient, which is based on the attenuation coefficient map (mu-map) created from a computed tomography scan, into the ordered...

    Authors: Yuya Nakamura, Seiji Tomiguchi and Masayuki Tanaka
    Citation: EJNMMI Physics 2015 2:17
    Content type: Original research article Published on:

  47. To assess differences between four different voxel-based dosimetry methods (VBDM) for tumor, liver, and lung absorbed doses following 90Y microsphere selective internal radiation therapy (SIRT) based on 90Y brems...

    Authors: Justin K Mikell, Armeen Mahvash, Wendy Siman, Firas Mourtada and S Cheenu Kappadath
    Citation: EJNMMI Physics 2015 2:16
    Content type: OriginalPaper Published on:

  48. Image registration algorithms are frequently used to align the reconstructed brain PET frames to remove subject head motion. However, in occupancy studies, this is a challenging task where competitive binding ...

    Authors: Jieqing Jiao, Graham E. Searle, Julia A. Schnabel and Roger N. Gunn
    Citation: EJNMMI Physics 2015 2:15
    Content type: Original research Published on:

  49. We present a study performing motion correction (MC) of PET using MR navigators sampled between other protocolled MR sequences during simultaneous PET/MR brain scanning with the purpose of evaluating its clini...

    Authors: Sune H Keller, Casper Hansen, Christian Hansen, Flemming L Andersen, Claes Ladefoged, Claus Svarer, Andreas Kjær, Liselotte Højgaard, Ian Law, Otto M Henriksen and Adam E Hansen
    Citation: EJNMMI Physics 2015 2:14
    Content type: Short communication Published on:

    The Erratum to this article has been published in EJNMMI Physics 2015 2:23

  50. Positron Emission Tomography (PET)-based automatic segmentation (PET-AS) methods can improve tumour delineation for radiotherapy treatment planning, particularly for Head and Neck (H&N) cancer. Thorough valida...

    Authors: B Berthon, C Marshall, R Holmes and E Spezi
    Citation: EJNMMI Physics 2015 2:13
    Content type: OriginalPaper Published on:
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