Table 1 Systematic comparison of the different methods applied
From: Multivariate analysis of PET pharmacokinetic parameters improves inferential efficiency
| Â | LME | PuMBA | SiMBA |
|---|---|---|---|
Modelling and statistical analysis | 2 consecutive steps | 2 consecutive steps | 1 step, simultaneously |
Input data | PK parameters | PK parameters | TACs |
Partial pooling | Univariate | Multivariate | Multivariate |
Inferential paradigm | Frequentist | Bayesian | Bayesian |
Computation time | Less than a second | Minutes | Hours to days |