Table 1 Correlation and agreement between BSIF- and IDIF-based CBF values
From: Image-derived input functions from dynamic 15O–water PET scans using penalised reconstruction
Region | Variable | Baseline | Acetazolamide |
|---|---|---|---|
Whole-brain GM CBF across subjects | Mean (SD) CBF (ml/cm3/min), BSIF | 0.64 (0.18) | 0.74 (0.14) |
Mean (SD) CBF (ml/cm3/min), IDIF | 0.63 (0.16) | 0.73 (0.14) | |
Correlation (R2) | 0.91 | 0.90 | |
Slope | 0.92 | 0.96 | |
Bias | − 2.5% | − 1.7% | |
Limits of agreement | − 17.8% | − 14.3% | |
12.9% | 10.9% | ||
SD of differences (ml/cm3/min) | 0.047 | 0.047 | |
CoV of differences | 7.3% | 6.4% | |
rCBF within subjects | Mean (SD) correlation (R2) | 0.99 (0.01) | 0.99 (0.01) |
Mean (SD) slope | 0.98 (0.16) | 0.98 (0.20) |