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EJNMMI Physics

Table 3 Relationship between benign and metastatic lesions in terms of SPECT and PET parameters in patients with prostate cancer

From: Quantitative [99mTc]Tc-MDP SPECT/CT correlated with [18F]NaF PET/CT for bone metastases in patients with prostate cancer

 

SPECT

PET

Benign

Metastatic

P value

Benign

Metastatic

P value

SUVmax

8.49 (6.45–10.45)

13.08 (7.25–24.40)

 < 0.001

19.04 (15.28–24.73)

32.99 (20.30–45.16)

 < 0.001

SUVpeak

7.58 (5.65–9.28)

11.68 (6.23–20.29)

 < 0.001

12.25 (9.68–15.14)

20.36 (13.60–30.90)

 < 0.001

SUVmean

6.35 (4.91–7.48)

7.58 (5.06–10.99)

0.005

11.74 (9.92–13.03)

15.42 (12.45–19.76)

 < 0.001

MBV

4.62 (2.41–8.22)

8.48 (3.11–15.66)

0.002

2.63 (1.52–5.12)

3.95 (1.87–10.02)

0.036

TBU

28.25 (13.07–63.06)

52.23 (17.47–176.62)

0.002

31.23 (16.94–66.51)

48.18 (24.58–187.31)

0.002

  1. Data are presented in terms of the median (IQR) values
  2. SUV Standardized uptake value, SUVmax Maximum SUV, SUVpeak Peak SUV, SUVmean Mean SUV, MBV Metabolic bone volume, TBU Total bone uptake
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