Fig. 1

PET radioactivity quantification in the presence of the MRI instrument. Phantoms with (a) 12.58 MBq (340 µCi) of fluorine-18 and (b) 11.1 MBq (300 µCi) of gallium-68, were each placed in the axial center of the PET insert. The insert was loaded into the MRI instrument, and a simultaneous PET/MRI scan was recorded every 30 min over a 12 h time period. Each data point represents the amount of activity extrapolated from an initial measurement with a dose calibrator or measured from the PET image for each 30 min time point. The black line represents a linear fit of the data. Phantoms with (c) 0.37–2.59 MBq (10–70 µCi) of fluorine-18 or (d) 0.37–1.67 MBq (10–45 µCi) of gallium-68 were placed in the axial center of the PET insert. The insert was loaded into the MRI instrument, and each tube was scanned for 30 min using simultaneous PET/MRI. The black line represents a linear fit of the data. (e) A Bland–Altman analysis was performed for the data in Fig. 1c. The bias was 0.173 (dashed line), which was not significantly different than 0 (p = 0.432). The 95% limits of agreement were ± 3.47 (dotted lines). Linear regression analysis produced a slope of − 0.054, which was significantly different than 0 (p = 0.024). (f) A Bland–Altman analysis was performed for the data in Fig. 1d. The bias was 0.030 (dashed line), which was not significantly different than 0 (p = 0.489). The 95% limits of agreement were ± 3.30 (dotted lines). Linear regression analysis produced a slope of 0.183, which was significantly different than 0 (p = 1.17 × 10^–5)