Fig. 7

Boxplots of percentages of dose difference (PDD) between absorbed doses estimated with the STP-Intra method (M2) at 24H and absorbed doses estimated with the reference method (tri-exponential function for fitting TDRC) for each VOI: LK, RK, L, S, L2 to L4, L1 to L5 and T9 to L5. Each boxplot includes PDD of the validation cohort at 24H of cycle 4 (TDRC of cycle 1 is used to estimate absorbed doses at cycle 4 from the acquisition at 24H). PDD are also calculated for the patient 10 of the patient cohort between cycles 3 and 4 (red, black and blue crosses for, respectively, 1H, 24H and 96H). For the two other time-points (6H in red and 7D in blue), PDD are estimated from the validation cohort only and medians of PDD are represented by circles