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Fig. 7 | EJNMMI Physics

Fig. 7

From: 166Holmium–99mTechnetium dual-isotope imaging: scatter compensation and automatic healthy-liver segmentation for 166Holmium radioembolization dosimetry

Fig. 7

Dependence of 99mTc scatter correction on 166Ho reconstructions. Scatter contributions from 99mTc on 166Ho image reconstructions are corrected for using a dual-energy-window scatter correction. The scatter is estimated from the 118-keV energy window, positioned in between the 166Ho and 99mTc photopeak, scaled by a k-factor. This graph shows the measured count density difference in 166 Ho reconstructions from 166Ho to 99mTc dual-isotope acquisitions relative to 166Ho-only acquisitions, as function of the k-factor. Each boxplot represents the results for the 26 patient procedures. Count density was evaluated within the healthy-liver volume. Outlier values were due to a higher-than-average 166Ho concentration in the liver (due to either higher activity or relatively small liver volume). The blue crosses show the equivalent metric for the phantom study, where the count density difference was evaluated for a 99mTc activity of 50 MBq

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