Fig. 2From: A novel semiautomated method for background activity and biological tumour volume definition to improve standardisation of 18F-FET PET imaging in glioblastomaRepresentative images and segmentations obtained with the two background assessment methods. Top–bottom: 18F-FET PET images of ten GBM patients; 18F-FET TBR images with overlays of BTV (red) and CTRL VOI (green) obtained with the gCS method; 18F-FET TBR images with overlays of BTV (red) and CTRL VOI (green) obtained with the MI method. BTV = biological tumour volume; CTRL = contralateral background reference region; FET = 18F-Fluoroethyl-l-tyrosine; TBR = tumour-to-brain ratio; VOI = volume of interestBack to article page