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Table 2 AICc values and weights after applying the IBMS method in patients P1, P3 and P4 with biokinetic data of five time points

From: A population-based method to determine the time-integrated activity in molecular radiotherapy

No Function AICc weight (%)a
P1 P3 P4
1 \(f_{2a}\)b
2 \(f_{2b}\) 100 60 100
3 \(f_{2c}\)b
4 \(f_{2d}\)b
5 \(f_{2e}\)b
6 \(f_{3a}\) 0 40 0
7 \(f_{3b}\)c
8 \(f_{3c}\) 0 0 0
9 \(f_{3d}\)c
10 \(f_{2a,3d}\)
11 \(f_{2b,3d}\)b
12 \(f_{2c,3d}\)b
  1. Equations (13)–(18) with shared parameters, which are designed for PBMS, were not included in the IBMS analysis. Function (19) failed based on visual inspection. For function (20) AICc could not be calculated as there are 4 fit parameters for only 5 data (compare Eq. (21))
  2. aAll the zeros stand for values lower than 10–5
  3. bThe fitting failed based on visual inspection of the graph
  4. cInadequate goodness of fit (these functions should not be used for model selection)