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EJNMMI Physics
Fig. 5 | EJNMMI Physics

Fig. 5

From: Nonclinical study and applicability of the absorbed dose conversion method with a single biodistribution measurement for targeted alpha-nuclide therapy

Fig. 5

Behavior maps of an optimal timing (solid line) on radiolabeled target compounds with a physical HL of 10 d. TpA1 and TbA1 are the physical HL and HL of the biological clearance of a target, respectively. a HL of the biological clearance of a reference, TbA2, of 25 h. b HL of the biological clearance of a reference, TbA2, of 1 h. The dashed and dotted lines represent optimal timing in the cases of 0.95 and 1.05, and 0.9 and 1.1 times converted absorbed doses, respectively

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