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Fig. 1 | EJNMMI Physics

Fig. 1

From: Nonclinical study and applicability of the absorbed dose conversion method with a single biodistribution measurement for targeted alpha-nuclide therapy

Fig. 1

Comparison between converted absorbed doses of [131I]MIBG [8], [211At]MABG [9], [125I]MIBG [10], and [77Br]MBBG [10] and the true target absorbed dose of [211At]MABG [8]. a Converted absorbed doses from [131I]MIBG [8] as a reference, and absorbed dose of [211At]MABG [8] as a true target. [131I]MIBG [8] indicates the absorbed dose of an organ or tumor tissue when alpha rays derived from 211At were emitted by the number of radioactive decays of 131I. “with half-life (HL)” shows a converted absorbed dose of [131I]MIBG [8] corrected by the physical half-life of 211At, indicating the physical part of Eq. (5).“with HL + RAtio of Pharmacokinetics (RAP)” is an absorbed dose of “with HL” converted using the representative RAP coefficient. b Same as (a) except that [211At] MABG [9] is a reference. c Same as (a) except that [125I]MIBG [10] is a reference. d Same as (a) except that [77Br]MBBG [10] is a reference

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