Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium–zinc–telluride-based SPECT/CT system: a phantom study

EJNMMI Physics

Table 3 Comparison of per cent contrasts (%) of all spheres among three different correction combinations

	Correction combination	37 mm	28 mm	22 mm	17 mm	13 mm	10 mm	P value
32:1	AC + SC + RR	88.95	80.36	77.35	71.82	59.65	54.13
	AC + RR	73.37	65.86	64.64	56.71	46.45	43.12	< 0.001^a
	AC + SC	58.30	42.81	32.41	15.69	8.91	7.41	< 0.001^b
16:1	AC + SC + RR	92.82	79.25	85.58	62.21	59.91	48.74
	AC + RR	76.85	64.98	71.41	51.78	51.15	37.85	< 0.001^a
	AC + SC	80.79	66.69	60.76	43.97	28.20	23.83	0.001^b
8:1	AC + SC + RR	78.65	71.05	64.37	57.63	43.49	39.34
	AC + RR	69.73	65.77	50.55	52.58	37.50	32.00	0.002^a
	AC + SC	77.93	63.92	38.94	38.93	28.40	22.11	0.011^b
4:1	AC + SC + RR	99.94	76.67	72.83	66.09	45.03	65.30
	AC + RR	80.81	62.67	64.85	51.79	39.67	45.96	0.002^a
	AC + SC	77.03	63.33	41.89	38.29	9.28	40.53	< 0.001^b

Reconstruction parameters: 35 iterations, 20 subsets, no filter; Acquisition parameters: 120 s/frame of acquisition time, 15% energy window; AC, attenuation correction; SC, scatter correction; RR, resolution recovery correction; a, AC + SC + RR vs. AC + RR; b, AC + SC + RR vs. AC + SC