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Table 3 SUVmax ratio and ΔHU comparisons for various groups of lesions

From: Data-driven gated PET/CT: implications for lesion segmentation and quantitation

  PET/ACT DDG-PET DDG-PET/CT
\(\tilde{x }\)± σ p \(\tilde{x }\)± σ p \(\tilde{x }\)± σ p
SUVmax ratio
Volume < 3 cc 1.31 ± 0.52 *** 1.31 ± 0.24 *** 1.96 ± 0.76 ***
Volume > 3 cc 1.13 ± 0.26 ** 1.19 ± 0.21 *** 1.64 ± 0.44 ***
Small versus large volume 0.02 0.02 *
HU < 0 1.35 ± 0.48 *** 1.27 ± 0.26 *** 2.01 ± 0.69 ***
HU > 0 1.04 ± 0.20 0.04 1.24 ± 0.19 *** 1.44 ± 0.26 ***
HU < 0 versus HU > 0 *** 0.33 ***
Lesion ΔHU
Volume < 3 cc 322 ± 352 *** − 4.9 ± 139 0.17 562 ± 395 ***
Volume > 3 cc 20.2 ± 182 * − 25.2 ± 168 * 50.5 ± 206 **
Small versus Large Volume ** * **
HU < 0 322 ± 321 *** − 32.1 ± 161 * 461 ± 339 ***
HU > 0 5.6 ± 25.7 0.02 -0.7 ± 138 0.53 4.4 ± 25.4 0.03
HU < 0 versus HU > 0 *** *** ***
  1. \(\tilde{x }\) = median, σ = standard deviation, cc = cm3, ΔHU = change in mean HU
  2. Tests of significance (p) are relative to baseline PET/CT except those labeled with
  3. SUVmax ratio and ΔHU values are calculated relative to baseline PET/CT
  4. baseline volume < 3 cc (n = 45), baseline volume > 3 cc (n = 46)
  5. baseline HU < 0 (n = 53), baseline HU > 0 (n = 38)
  6. *p < 0.01, **p < 0.001, ***p < 0.0001